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    Foye's principles of medicinal chemistry / edited by Thomas L. Lemke, David A. Williams ; assistant editors, Victoria F. Roche, S. William Zito.

    • Title:Foye's principles of medicinal chemistry / edited by Thomas L. Lemke, David A. Williams ; assistant editors, Victoria F. Roche, S. William Zito.
    •    
    • Variant Title:Principles of medicinal chemistry
    • Other Contributors/Collections:Foye, William O.
      Lemke, Thomas L.
      Williams, David A., 1938-
    • Published/Created:Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, ©2008.
    • Holdings

       
    • Library of Congress Subjects:Pharmaceutical chemistry.
    • Medical Subjects: Chemistry, Pharmaceutical.
    • Edition:6th ed.
    • Description:xiv, 1377 p. : ill. (some col.) ; 29 cm.
    • Notes:Includes bibliographical references and indexes.
    • ISBN:9780781768795
    • Contents:1. Historical Perspective of Medicinal Chemistry / John L. Neumeyer
      Pt. I. Principles of Drug Discovery
      Ch. 1. Discovery from Natural Products / A. Douglas Kinghorn
      Ch. 2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity / James J. Knittel and Robin M. Zavod
      Ch. 3. Molecular Modeling and In Silico Drug Design / Xiang-Qun (Sean) Xie
      Ch. 4. Receptors and Drug Action / Timothy A. Maher and David A. Johnson
      Ch. 5. Drug Discovery Through Enzyme Inhibition / Stephen Kerr
      Ch. 6. Pharmaceutical Biotechnology - From Nucleic Acids to Personalized Medicine / Ronald E. Reid and Robert D. Sindelar
      Ch. 7. Peptide and Protein Drugs / Michael Mokotoff
      Ch. 8. Antisense Therapeutic Agents / Marilyn Speedie
      Ch. 9. Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics / Sunil S. Jambhekar
      Ch. 10. Drug Metabolism / David A. Williams
      Ch. 11. U.S. Drug Regulation: An Overview / Douglas J. Pisano
      Pt. II. Drug Receptors Affecting Neurotransmission and Enzymes as Catalytic Receptors
      Overview of Drug Receptors: A Perspective / David J. Triggle
      Ch. 12. Drugs Affecting Cholinergic Neurotransmission / E. Kim Fifer
      Ch. 13. Adrenergic Receptors and Drugs Affecting Adrenergic Neurotransmission / Robert K. Griffith
      Ch. 14. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission / Richard A. Glennon and Malgorzata Dukat-Glennon
      Ch. 15. Amino Acid Neurotransmitters in the Central Nervous System / Timothy J. Maher
      Ch. 16. Inhibitors of Nerve Conduction: Local Anesthetics / Matthias C. Lu
      Ch. 17. Phosphodiesterase Inhibitors / Kevin Dalby
      Pt. III. Pharmacodynamic Agents
      Ch. 18. General Anesthetics / Timothy J. Maher
      Ch. 19. Sedative-Hypnotics / William Soine
      Ch. 20. Antiseizure Agents / Barbara Leduc
      Ch. 21. Antidepressants / David A. Williams
      Ch. 22. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents / Raymond G. Booth
      Ch. 23. Hallucinogens, Stimulants and Related Drugs of Abuse / Richard A. Glennon
      Ch. 24. Opioid Analgesics / David S. Fries
      Ch. 25. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents / Raymond G. Booth
      Ch. 26. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs / Ahmed S. Mehanna
      Ch. 27. Diuretics / Gary O. Rankin
      Ch. 28. Angiotensin-Converting Enzyme Inhibitors, Antagonists and Calcium Blockers / Marc Harrold
      Ch. 29. Central and Peripheral Sympatholytics and Vasodilators / David A. Williams
      Ch. 30. Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis / Marc Harrold
      Ch. 31. Antithrombotics, Thrombolytics, Coagulants, and Plasma Extenders / Matthias C. Lu and Thomas L. Lemke
      Ch. 32. Insulin and Drugs Used for the Treatment of Diabetes / Robin M. Zavod, John L. Krstenansky and Bruce L. Currie
      Ch. 33. Adrenocorticoids / Duane D. Miller, Robert W. Brueggemeier and James T. Dalton
      Ch. 34. Thyroid Function and Thyroid Drugs / Ali R. Banijamali
      Ch. 35. Calcium Homeostasis / Robin M. Zavod
      Ch. 36. Nonsteroidal Anti-Inflammatory Drugs / Ronald Borne, Mark Levi and Norman Wilson
      Ch. 37. Antihistamines and Related Antiallergic and Antiulcer Agents / Wendel L. Nelson
      Ch. 38. Antibiotics and Antimicrobial Agents / Lester A. Mitscher, Thomas L. Lemke and Elmer J. Gentry
      Ch. 39. Antiparasitic Agents / Thomas L. Lemke
      Ch. 40. Antifungal Agents / Robert K. Griffith
      Ch. 41. Antimycobacterial Agents / Thomas L. Lemke
      Ch. 42. Cancer and Chemotherapy / Victoria F. Roche
      Ch. 43. Antiviral Agents and Protease Inhibitors / Patrick M. Woster
      Pt. IV. Disease State Management
      Ch. 44. Asthma and Chronic Obstructive Pulmonary Disease / S. William Zito
      Ch. 45. Men's Health / Duane D. Miller, Robert W. Brueggemeier and James T. Dalton
      Ch. 46. Women's Health / Robin M. Zavod
      App. A. pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases
      App. B. pH Values for Tissue Fluids.
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