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    Principles of pharmacology : the pathophysiologic basis of drug therapy / David E. Golan [and others].

    • Title:Principles of pharmacology : the pathophysiologic basis of drug therapy / David E. Golan [and others].
    •    
    • Other Contributors/Collections:Golan, David E.
    • Published/Created:Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, ©2012.
    • Holdings

       
    • Library of Congress Subjects:Pharmacology.
      Physiology, Pathological.
    • Medical Subjects: Pharmacological Phenomena.
      Drug Therapy.
    • Edition:3rd ed.
    • Description:xxi, 954 pages : illustrations (chiefly color) ; 28 cm.
    • Summary:Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient.
      Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text:
      Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow.
      Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations.
      Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative.
      Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action.
      Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty --Book Jacket.
    • Notes:Includes bibliographical references and index.
    • ISBN:9781608312702
      1608312704 (alk. paper)
    • Contents:Section I. Fundamental principles of pharmacology
      Drug-receptor interactions / Zachary S. Morris and David E. Golan
      Pharmacodynamics / Quentin J. Baca and David E Golan
      Pharmacokinetics / Quentin J. Baca and David E. Golan
      Drug metabolism / Cullen Taniguchi and F. Peter Guengerich
      Drug toxicity / Michael W. Conner ... [et.al.]
      Pharmacogenomics / Liewei Wang and Richard M. Weinshilboum. Section II. Principles of neuropharmacology
      Section IIA. Fundamental principles of neuropharmacology
      Principles of cellular excitability and electrochemical transmission / Lauren K. Buhl, John Dekker, and Gary R. Strichartz
      Principles of nervous system physiology and pharmacology / Joshua M. Galanter, Susannah B. Comes, and Daniel H. Lowenstein
      Section IIB. Principles of autonomic and peripheral nervous system pharmacology
      Cholinergic pharmacology / Alireza Atri, Michael S. Chang, and Gary R. Strichartz
      Adrenergic pharmacology / Brian B. Hoffman and Freddie M. Williams
      Local anesthetic pharmacology / Joshua M. Schulman and Gary R. Strichartz
      Section IIC. Principles of central nervous system pharmacology
      Pharmacology of GABAergic and glutamatergic neurotransmission / Stuart A. Forman ... [et.al.]
      Pharmacology of dopaminergic neurotransmission / David G. Standaert and Ryan R. Walsh
      Pharmacology of serotonergic and central adrenergic neurotransmission / Miles Berger and Bryan Roth
      Pharmacology of abnormal electrical neurotransmission in the central nervous system / Susannah B. Comes, Edmund A. Griffin, Jr., and Daniel H. Lowenstein
      General anesthetic pharmacology / Jacob Wouden and Keith W. Miller
      Pharmacology of analgesia / Robert S. Griffin and Clifford J. Woolf
      Pharmacology of drugs of abuse / Peter R. Martin, Sachin Patel, and Robert M. Swift. Section III. Principles of cardiovascular pharmacology
      Pharmacology of cholesterol and lipoprotein metabolism / David E. Cohen and Ehrin J. Armstrong
      Pharmacology of volume regulation / Mallar Bhattacharya and Seth L. Alper
      Pharmacology of vascular tone / Deborah Yeh Chong and Thomas Michel
      Pharmacology of hemostasis and thrombosis / April W. Armstrong and David E. Golan
      Pharmacology of cardiac rhythm / Ehrin J. Armstrong, April W. Armstrong, and David E. Clapham
      Pharmacology of cardiac contractility / Ehrin J. Armstrong and Thomas P. Rocco
      Integrative cardiovascular pharmacology: Hypertension, ischemic heart disease, and heart failure / Ehrin J. Armstrong, April W. Armstrong, and Thomas P. Rocco. Section IV. Principles of endocrine pharmacology
      Pharmacology of the hypothalamus and pituitary gland / Anand Vaidya and Ursula B. Kaiser
      Pharmacology of the thyroid gland / Ehrin J. Armstrong, Armen H. Tashjian, and William W. Chin
      Pharmacology of the adrenal cortex / Rajesh Garg and Gail K. Adler
      Pharmacology of reproduction / Ehrin J. Armstrong and Robert L. Barbieri
      Pharmacology of the endocrine pancreas and glucose homeostasis / Aimee D. Shu and Steven E. Shoelson
      Pharmacology of bone mineral homeostasis / Robert M. Neer, Ehrin J. Armstrong, and Armen H. Tashjian, Jr. Section V. Principles of chemotherapy
      Principles of antimicrobial and antineoplastic pharmacology / Quentin J. Baca, Donald M. Coen, and David E. Golan
      Pharmacology of bacterial infections: DNA replication, transcription, and translation / Marvin Ryou and Donald M. Coen
      Pharmacology of bacterial and mycobacterial infections: Cell wall synthesis / Tania Lupoli ... [et.al.]
      Pharmacology of fungal infections / Ali Alikhan, Charles R. Taylor, and April W. Armstrong
      Pharmacology of parasitic infections / Louise C. Ivers and Edward T. Ryan
      Pharmacology of viral infedctions / Robert W. Yeh and Donald M. Coen
      Pharmacology of cancer: Genome synthesis, stability, and maintenance / David A. Barbie and David A. Frank
      Pharmacology of cancer: Signal transduction / David A. Barbie and David A. Frank
      Principles of combination chemotherapy / Quentin J. Baca, Donald M. Coen, and David E. Golan. Section VI. Principles of inflammation and immune pharmacology
      Principles of inflammation and the immune system / Ehrin J. Armstrong and Lloyd B. Klickstein
      Pharmacology of eicosanoids / David M. Dudzinski and Charles N. Serhan
      Histamine pharmacology / Cindy Chambers, Joseph C. Kvedar, and April W. Armstrong
      Pharmacology of hematopoiesis and immunomodulation / Andrew J. Wagner, Ramy A. Arnaout, and George D. Demetri
      Pharmacology of immunosuppression / April W. Armstrong, Ehrin J. Armstrong, and Lloyd B. Klickstein
      Integrative inflammation pharmacology: Peptic ulcer disease / Dalia S. Nagel and Helen M. Shields
      Integrative inflammation pharmacology: Asthma / Joshua M. Galanter and Stephen Lazarus
      Integrative inflammation pharmacology: Gout / Ehrin J. Armstrong and Lloyd B. Klickstein. Section VII. Fundamentals of drug development and regulation
      Drug discovery and preclinical development / John L. Vahle ... [et.al.]
      Clinical drug evaluation and regulatory approval / Mark A. Goldberg, Alexander E. Kuta, and John L. Vahle
      Systematic detection of adverse drug events / Jerry Avom. Section VIII. Environmental toxicology
      Environmental toxicology / Laura C. Green ... [et.al Section IX. Frontiers in pharmacology
      Protein therapeutics / Quentin J. Baca, Benjamin Leader, and David E. Golan
      Drug delivery modalities / Joshua D. Moss and Robert S. Langer.
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