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Mims' medical microbiology.
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Title:Mims' medical microbiology.
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Variant Title:Medical microbiology
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Other Contributors/Collections:Goering, Richard V.
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Published/Created:[London] : Elsevier/Saunders, ©2013.
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Holdings
Holdings Record Display
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Location:BMB LIBRARY (VGH) stacksWhere is this?
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Call Number: WC100 .M6625 2013
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Number of Items:1
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Status:Available
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Location:OKANAGAN LIBRARY stacksWhere is this?
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Call Number: WC100 .M6625 2013
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Number of Items:1
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Status:Available
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Location:WOODWARD LIBRARY stacksWhere is this?
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Call Number: WC100 .M6625 2013
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Number of Items:1
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Status:Available
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Location:BMB LIBRARY (VGH) stacksWhere is this?
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Library of Congress Subjects:Medical microbiology.
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Medical Subjects: Communicable Diseases--microbiology.
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Edition:5th ed. / Richard V. Goering ... [et al.].
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Description:xiv, 565 pages : illustrations (chiefly color) ; 28 cm.
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Summary:Using a clinically relevant, systems-based approach, this medical textbook accessibly explains the microbiology of the agents that cause diseases and the diseases that affect individual organ systems. With lavish illustrations and straightforward, accessible explanations, Richard Goering makes this complex subject simple to understand and remember. 150 multiple choice review questions. "Pathogen Parade" and many other features to enhance learning and retention. Enhance your learning and absorb complex information in an interactive, dynamic way. Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventive medicine. A completely re-written chapter on this topic keeps abreast of the very latest findings.
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Notes:Previous ed.: London: Mosby, 2008.
Includes Internet access.
Includes bibliographical references and index.
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ISBN:9780723436010 (pbk.)
0723436010 (pbk.)
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Contents:Machine generated contents note: SECTION 1 ADVERSARIES-MICROBES
1. Microbes as parasites
varieties of microbes
Living inside or outside cells
Systems of classification
2. bacteria
Structure
Nutrition
Growth and division
Gene expression
Survival underadverse conditions
Mobile genetic elements
Mutation and gene transfer
genomics of medically important bacteria
3. viruses
Infection of host cells
Replication
Outcome of viral infection
Major groups of viruses
4. fungi
Major groups of disease-causing fungi
5. protozoa
6. helminths and arthropods
helminths
arthropods
7. Prions
`Rogue protein' pathogenesis
Development, transmission and diagnosis of prion diseases
Prevention and treatment of prion diseases
8. host-parasite relationship
normal flora
Symbiotic associations
characteristics of parasitism
evol ution of parasitism
SECTION 2 ADVERSARIES-HOST DEFENCES
9. innate defences of the body
Defence against entry into the body
Defences once the microorganism penetrates the body
10. Adaptive responses provide a `quantum leap' in effective defence
role ofantibodies
role of Tlymphocytes
Extracellular attack on large infectious agents
Local defences at mucosal surfaces
11. cellular basis of adaptive immune responses
B- and T-cell receptors
Clonal expansion of lymphocytes
role of memory cells
Stimulation of lymphocytes
Cytokines
Regulatory mechanisms
Tolerance mechanisms
SECTION 3 CONFLICTS
12. Background to the infectious diseases
Host-parasite relationships
Causes of infectious diseases
biologic response gradient
13. Entry, exit and transmission
Sites of entry
Exit and transmission
Types of transmission between humans
Transmission from animals
14. Immune defences in action
Complement
Acute phase proteins and pattern recognition receptors
Fever
Natural killer cells
Phagocytosis
Cytokines
Antibody-mediated immunity
Cell-mediated immunity
Recovery from infection
15. Spread and replication
Features of surface and systemic infections
Mechanisms of spread through the body
Genetic determinants of spread and replication
Other factors affecting spread and replication
16. Parasite survival strategies and persistent infections
Parasite survival strategies
Antigenic variation
Immunosuppression
Persistent infections
17. Pathologic consequences of infection
Pathology caused directly by microorganism
Diarrhea
Pathologic activation of natural immune mechanisms
Pathologic consequences of the immune response
Skin rashes
Viruses and cancer
SECTION 4 CLINICAL MANIFESTATION AND DIAGNOSIS OF INFECTIONS BY BODY SYSTEM
Introduction to Section 4: The clinical manifestations of infection
18. Upper respiratory tract infections
Rhinitis
Pharyngitis and tonsillitis
Parotitis
Otitis and sinusitis
Acute epiglottitis
Oral cavity infections
19. Lower respiratory tract infections
Laryngitis and tracheitis
Diphtheria
Whooping cough
Acute bronchitis
Acute exacerbations of chronic bronchitis
Bronchiolitis
Respiratory syncytial virus infection
Hantavirus pulmonary syndrome (HPS)
Pneumonia
Bacterial pneumonia
Viral pneumonia
Parainfluenza virus infection
Adenovirus infection
Human metapneumovirus
Human bocavirus
Influenza virus infection
Severe acute respiratory syndrome-associated coronavirus infection
Measles
Cytomegalovirus infection
Tuberculosis
Cystic fibrosis
Lung abscess
Fungal infections
Parasitic infections
20. Urinary tract infections
Acquisition and aetiology
Pathogenesis
Clinical features and complications
Laboratory diagnosis
Treatment
Prevention
21. Sexually transmitted infections
STIs and sexual behaviour
Syphilis
Gonorrhoea
Chlamydial infection
Other causes of inguinal lymphadenopathy
Mycoplasmas and non-gonococcal urethritis
Othercauses ofvaginitis and urethritis
Genital herpes
Human papillomavirus infection
Human immunodeficiency virus
Opportunist STIs
Arthropod infestations
22. Gastrointestinal tract infections
Diarrheal diseases caused by bacterial or viral infection
Food poisoning
Helicobacter pylori and gastric ulcer disease
Parasites and the gastrointestinal tract
Systemic infection initiated in the gastrointestinal tract
23. Obstetric and perinatal infections
Infections occurring in pregnancy
Congenital infections
Infections occurring around thetime of birth
24. Central nervous system infections
Invasion of the central nervous system
body's response to invasion
Meningitis
Encephalitis
Neurologic diseases of possible viral aetiology
Spongiform encephalopathies caused by scrapie-type agents
CNS disease caused by parasites
Brain abscesses
Tetanus and botulism
25. Infections of the eye
Conjunctivitis
Infection of the deeper layers of the eye
26. Infections of the skin, soft tissue, muscle and associated systems
Bacterial infections of skin, soft tissue and muscle
Mycobacterial diseases of the skin
Fungal infections of the skin
Parasitic infections of the skin
Mucocutaneous lesions caused by viruses
Smallpox
Measles
Rubella
Other infections producing skin lesions
Kawasaki syndrome
Viral infections of muscle
Parasitic infections of muscle
Joint and bone infections
Infections of the haemopoietic system
27. Vector-borne infections
Arbovirus infections
Infections caused by rickettsiae
Borrelia infections
Protozoal infections
Helminth infections
28. Multisystem zoonoses
Arenavirus infections
Haemorrhagic fever with renal syndrome (HFRS)
Marburg and Ebola haemorrhagic fevers
Crimean-Congo haemorrhagic fever, a tick-borne virus
Q fever
Anthrax
Plague
Yersinia enterocolitica infection
Tularemia
Pasteurellamultocida infection
Leptospirosis
Rat-bite fever
Brucellosis
Helminth infections
29. Fever of unknown origin
Definitions of fever of unknown origin
Causes of FUO
Investigation of classic FUO
Treatment of FUO
FUO in specific patient groups
Infective endocarditis
30. Infections in the compromised host
compromised host
Infections ofthe host with deficient innate immunity due to physical factors
Infections associated with secondary adaptive immunodeficiency
Other important opportunist pathogens
SECTION 5 DIAGNOSIS AND CONTROL
31. Diagnosis of infection and assessment of host defense mechanisms
Aims of the clinical microbiology laboratory
Specimen processing
Non-cultural techniques for the laboratory diagnosis of infection
Cultivation (culture) of microorganisms
Identification of microorganisms grown in culture
Antibody detection methods for the diagnosis of infection
Assessment of host defence systems
Putting it all together: detection, diagnosis, and epidemiology
32. Epidemiology and control of infectious diseases
Outcome measurements
Types of epidemiological studies
Transmission of infectious disease
Vaccine efficacy
33. Attacking the enemy: antimicrobial agents and chemotherapy
Selective toxicity
Discovery and design of antimicrobial agents
Classification of antibacterial agents
Resistance to antibacterial agents
Classes of antibacterial agents
Inhibitors of cell wall synthesis
Inhibitors of protein synthesis
Inhibitors of nucleic acid synthesis
Antimetabolites affecting nucleic acid synthesis
Other agents that affect DNA
Inhibitors of cytoplasmic membrane function
Urinary tract antiseptics
Antituberculosis agents
Antibacterial agents in practice
Antibiotic assays
Antiviral therapy
Antifungal agents
Antiparasitic agents
Control by chemotherapy versus vaccination
Control versus eradication
Use and misuse of antimicrobial agents
34. Protecting the host: vaccination
vaccination - A four hundred year history
Aims of vaccination
Vaccines can be of different types
35. Passive and non-specific immunotherapy
Passive immunization with antibody
Non-specific cellular immunostimulation
Correction of host immunodeficiency
Probiotics
36. Hospital infection, sterilization and disinfection
Common hospital infections
Important causes of hospital infection
Sources and routes of spread of hospital infection
Host factors and hospital infection
Consequences of hospital infection
Prevention of hospital infection
Investigating healthcare-associated infection
Sterilization and disinfection.