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    The evolution of vertebrate blood clotting / Russell F. Doolittle.

    • Title:The evolution of vertebrate blood clotting / Russell F. Doolittle.
    •    
    • Author/Creator:Doolittle, Russell F., 1931-2019.
    • Published/Created:Mill Valley, Calif. : University Science Books, ©2013.
    • Holdings

       
    • Library of Congress Subjects:Blood--Coagulation.
      Fibrinogen.
    • Medical Subjects: Blood Coagulation--physiology.
      Fibrinogen--genetics.
    • Description:xiii, 221 pages : illustrations (some color) ; 24 cm
    • Summary:"This book charts the step-by-step evolution of vertebrate blood coagulation. Intended for readers with a background in biological science, it is specifically targeted for those in the field of molecular evolution and researchers in the area of blood clotting. The orderly way in which gene duplications provided new genes for fine-tuning the system serves as a model for how complex physiological systems in general have evolved. The book includes suggestions for specific genetic engineering experiments that can be done to illustrate how molecular evolution works"--Publisher's description.
    • Notes:Includes index.
      Includes bibliographical references and index.
    • ISBN:9781891389818 (hbk. : alk. paper)
      1891389815 (hbk. : alk. paper)
    • Contents:Machine generated contents note: pt. I LAYING THE GROUNDWORK
      ch. 1 Blood Clotting in Humans
      ch. 2 Clotting Inhibitors and Fibrinolysis
      ch. 3 Localizing Clots
      ch. 4 Proteins and Domains
      ch. 5 Fibrinogen and Fibrin
      ch. 6 Animals, Their Proteins, and Phylogenetics
      ch. 7 Gene Duplications
      ch. 8 Genomes
      pt. II SEARCHING THROUGH GENOMES
      ch. 9 Genomes of Fish with Jaws
      ch. 10 Lamprey Clotting Genes
      ch. 11 Contact Factors and Other Embellishments
      ch. 12 Protochordate Genomes
      ch. 13 Getting the System Started.
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