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    Gene regulation / Gurbachan S. Miglani.

    • Title:Gene regulation / Gurbachan S. Miglani.
    •    
    • Author/Creator:Miglani, Gurbachan S., author.
    • Published/Created:Oxford, U.K. : Alpha Science International Ltd., [2013]
      c2013
    • Holdings

       
    • Library of Congress Subjects:Genetic regulation.
    • Medical Subjects: Gene Expression Regulation.
    • Description:1 volume (in various pagings) : illustrations ; 25 cm
    • Notes:Includes bibliographical references and index.
    • ISBN:1842658204
      9781842658208
    • Contents:Machine generated contents note: 1. Introduction
      Genetic Material
      Organization of Genetic Material
      Gene Organization
      Gene Structure and Function
      Gene Expression
      Gene Regulation
      References
      2. Gene Regulation in Bacteria
      Gene Regulation at DNA Level
      Gene Regulation at Transcriptional Level
      Antisense RNA in Prokaryotic Gene Regulation
      Alternative Sigma Factors
      Post-Transcriptional Control
      Control at Translational Level
      Post-Translational Control
      Multiple Small RNAs as Essential Regulators
      Alarmones
      References
      3. Gene Regulation in Viruses
      SpoI Bacteriophage
      Lambda Bacteriophage
      T4 Bacteriophage
      T7 bacteriophage
      Human Immunodeficiency Virus
      Varicella-Zoster Virus
      4. Gene Regulation in Eukaryotes
      Gene Control Levels in Eukaryotic Cells
      Transcriptional Initiation in Mammalian Genes
      Gene Squelching
      Messenger RNA and Differentiation
      Small Molecules in Regulation of Gene Expression
      Molecular Zippers in Gene Regulation
      Gene Regulation by Non-Histone Proteins
      Artificial Gene Repressors
      Specificity in Eukaryotic Gene Transcription
      Metal-Regulated Transcription in Eukaryotes
      Smart Genes
      Choice of Transcriptional Repression or Activation
      Circadian Clock
      Noise and Gene Expression
      Regulatory Code Akin to The Genetic Code
      Transcriptional Regulatory Networks
      Control of Cell Cycle
      Cohesion Complex Regulates Gene Expression
      Reference
      5. Models of Gene Regulation
      Gene Regulation by Hormonal Action
      Protein-Nucleic Acid Interactions in Gene Regulation
      Gene Regulatory Network Modeling
      Mated Model of Gene Regulation in Eukaryotes
      Coordinated Gene Expression
      Synthetic Networks
      References
      6. Methylation of Nucleic Acids and Gene Regulation
      Bacterial Methylase Systems
      Characteristics of DNA Methylation
      Possible Functions of DNA Methylation
      Host Restriction and Modification
      Cytosine Methylation in Vertebrates
      Epigenetics
      DNA Methylation and Gene Expression
      DNA Methylation in Gene Regulation and Differentiation
      Heterochromatin Formation
      Paternal X chromosome Inactivation
      DNA Methylation in Invertebrates
      DNA Methylation in Plants
      Defense Against Spread of Transposable Elements
      Cyclical Changes in DNA Methylation
      RNA Methylation
      References
      7. Histone Modification and Gene Regulation
      Histone Modification Enzymes
      Histone Methylation
      Histone Demethylation
      Histone Acetylation
      Histone Deacetylation
      Histone Phosphorylation
      Histone Ubiquitination
      Ploy(ADP-Ribosyl)ation
      Gene Regulation by Histones
      Histone Replacement
      Histone Turnover
      Consequences of Histone Modifications
      DNA and Histone Methylation
      References
      8. Gene Silencing
      RNomics and Gene Regulation
      Gene Silencing
      Transcriptional Gene Silencing
      RNA-Directed DNA Methylation
      Genome Imprinting
      Paramutation
      Transposon Silencing
      Hybrid Dysgenesis
      Position Effect Variegation
      Transvection
      Transinduction
      Monoallelic Gene Expression
      Post-Transcriptional Gene Silencing
      RNA Interference
      RNA Interference-Directed Chromatin Modification
      Quelling
      Co-suppression
      Non-Sense Mediated mRNA Decay
      Virus-Induced Gene Silencing
      Riboswitches
      Transgene Silencing
      Methylation of Non-Coding RNAs
      DNA Mimics
      Translational Gene Silencing
      Exploitation of Gene Silencing
      References
      9. Modifying and Modulating Gene Expression, and Exploiting Gene Regulation
      Modifying Gene Expression
      Modulating Gene Expression
      Exploiting Gene Regulation
      References
      10. Molecular Basis of Evolution
      Evolutionarily Important Genes
      Molecular Evolutionary Clock
      Genome Organization and Evolution
      Selfish DNA
      Establishment of New Patterns of Gene Control
      Epochs of Molecular Evolution
      Molecular Information in Evolutionary Studies
      Basis of Molecular Evolution
      Reproductive Protein Evolution
      Molecular Evidence of Large Evolutionary Changes
      Origin of Species
      Forces of Molecular Evolution
      "Neutralist-Selectionist" Debate
      Proteome
      Cryptic Genetic Variation
      Epistatic Interactions
      Degeneracy and Evolution
      References
      11. Molecular Basis of Development
      Preformation versus Epigenesis
      Ontogenic and Phylogenic Development
      Biogenetic Law
      Mosaic and Regulation Eggs
      Regulation of Development
      Role of Genes in Development
      Understanding Development in Genetics Terms
      Totipotency and Development
      Pattern Formation
      Epigenetics in Development
      Morphogenesis
      Animal Development
      Plant Development
      Developmental Machinery
      `Evo-Dovo' Concept
      Overview
      References
      12. Molecular Tools and Techniques
      DNA Fingerprinting
      DNA Markers
      Serial Analysis of Gene Expression
      DNA/RNA Chip (Microarrays) Technology
      DNA Nanotechnology
      Restriction Endonucleases
      Recombinant DNA Technology
      Identifying Unknown Proteins
      Yeast-Two Hybrid System
      Protein Chip Technology
      Quantitative Trait Loci Mapping
      References.
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