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• Title:[Fundamentals of clinical chemistry.]
  Tietz fundamentals of clinical chemistry and molecular diagnostics / Carl A. Burtis, David E. Bruns ; consulting editor Barbara G. Sawyer.
  
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• Variant Title:Fundamentals of clinical chemistry and molecular diagnostics.
  Clinical chemistry and molecular diagnostic
  
• Other Contributors/Collections:Burtis, Carl A., author.
  Bruns, David E., 1941- author.
  Sawyer, Barbara G.
  Tietz, Norbert W., 1926-
  
• Published/Created:St. Louis : Elsevier/Saunders, ©2015.
  

• Holdings

  Holdings Record Display

  • Location:BMB LIBRARY (VGH) stacksWhere is this?
    
  • Call Number: QY90 .F84 2015
    
  • Number of Items:1
    
  • Status:Available
    

  • Location:WOODWARD LIBRARY stacksWhere is this?
    
  • Call Number: QY90 .F84 2015
    
  • Number of Items:1
    
  • Status:Available
    

   
• Library of Congress Subjects: Clinical chemistry.
  Molecular diagnosis.
  
• Medical Subjects:Chemistry, Clinical.
  Pathology, Molecular.
  
• Edition:Seventh edition.
  
• Description:xxii, 1, 075 pages : illustrations ; 29 cm
  
• Summary:"For the laboratory science student, the professional laboratorian, and the practicing pathologist, this textbook serves as an outstanding resource for (1) the study of basic laboratory operations, (2) understanding clinical chemistry analytes, and (3) comprehending fundamental pathophysiology."--Page xiii.
  
• Notes:Revised edition of: Fundamentals of clinical chemistry / editor, Norbert W. Tietz. 3rd ed. 1987.
  Includes bibliographical references and index.
  
• ISBN:1455741655
  9781455741656
  
• Contents:Machine generated contents note: pt. I PRINCIPLES OF LABORATORY MEDICINE
  1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine / Carl A. Burtis
  Laboratory Medicine
  Clinical Chemistry and Laboratory Medicine
  Molecular Diagnostics
  Ethical Issues in Laboratory Medicine
  Review Questions
  2. Selection and Analytical Evaluation of Methods
  -With Statistical Techniques / James C. Boyd
  Method Selection
  Basic Statistics
  Basic Concepts in Relation to Analytical Methods
  Analytical Goals
  Method Comparison
  Monitoring Serial Results
  Traceability and Measurement Uncertainty
  Software Packages
  Review Questions
  3. Clinical Evaluation of Methods / David E. Bruns
  Sensitivity and Specificity
  Receiver Operating Characteristic Plots
  Probabilistic Reasoning
  Prevalence
  Predictive Values
  Odds Ratio
  Likelihood Ratio
  Bayes' Theorem
  Combination Testing
  Methods of Assessing Diagnostic Accuracy
  Review Questions
  4. Evidence-Based Laboratory Medicine / David E. Bruns
  Evidence-Based Medicine
  -What Is It?
  Evidence-Based Medicine and Laboratory Medicine
  Information Needs in Evidence-Based Laboratory Medicine
  Characterization of Diagnostic Accuracy Tests
  Outcomes Studies
  Systematic Reviews of Diagnostic Tests
  Economic Evaluations of Diagnostic Testing
  Clinical Practice Guidelines
  Clinical Audit
  Applying the Principles of Evidence-Based Laboratory Medicine in Routine Practice
  Review Questions
  5. Establishment and Use of Reference Values / Gary L. Horowitz
  Establishment of Reference Values
  Use of Reference Values
  Review Questions
  6. Specimen Collection, Processing, and Other Preanalytical Variables
  Doris M. Haverstick, and Amy R. Groszbach
  Types of Specimens
  Handling of Specimens for Analysis
  Review Questions
  7. Quality Management / James O. Westgard
  Fundamentals of Total Quality Management
  Implementing TQM
  Personnel Competency and Training
  Total Testing Process
  Control of Preanalytical Variables
  Control of Analytical Variables
  External Quality Assessment and Proficiency Testing Programs
  New Quality Initiatives
  Review Questions
  8. Principles of Basic Techniques and Laboratory Safety / Stanley F. ho
  Concept of Solute and Solvent
  Units of Measurement
  Chemicals
  Reference Materials
  Basic Techniques and Procedures
  Review Questions
  pt. II ANALYTICAL TECHNIQUES AND INSTRUMENTATION
  9. Optical Techniques / Jason Y. Park
  Photometry and Spectrophotometry
  Instrumentation
  Reflectance Photometry
  Atomic Absorption Spectrophotometry
  Fluorometry
  Phosphorimetry
  Luminometry
  Nephelometry and Turbidimetry
  Review Questions
  10. Electrochemistry and Chemical Sensors / Mark E. Meyerhoff
  Potentiometry
  Voltammetry/Amperometry
  Conductometry
  Coulometry
  Optical Chemical Sensors
  Biosensors
  Review Questions
  11. Electrophoresis / James P. Landers
  Basic Concepts and Definitions
  Theory of Electrophoresis
  Description of Technique
  Types of Electrophoresis
  Technical Considerations
  Review Questions
  12. Chromatography / Carl A. Burtis
  Basic Concepts
  Separation Mechanisms
  Planar Chromatography
  Column Chromatography
  Qualitative and Quantitative Analyses
  Review Questions
  13. Mass Spectrometry / Nicholas E. Sherman
  Basic Concepts and Definitions
  Instrumentation
  Clinical Applications
  Review Questions
  14. Enzyme and Rate Analyses / Mauro Pan-teghini
  Basic Principles
  Enzyme Kinetics
  Analytical Enzymology
  Review Questions
  15. Immunochemical Techniques / J.Y. Park
  Basic Concepts and Definitions
  Antigen-Antibody Binding
  Qualitative Methods
  Quantitative Methods
  Other Immunochemical Techniques
  Review Questions
  16. Automation / Charles D. Hawker
  Basic Concepts
  Automation of Analytical Processes
  Integrated Automation for the Clinical Laboratory
  Practical Considerations
  Other Areas of Automation
  Review Questions
  17. Point-of-Care Instrumentation / Andrew St. John
  Analytical and Technological Considerations
  Implementation and Management Considerations
  Review Questions
  pt. III ANALYTES
  18. Amino Acids, Peptides, and Proteins / Glen L. Hortin
  Amino Acids
  Peptides and Proteins
  Analysis of Proteins
  Plasma and Serum Proteins
  Review Questions
  19. Serum Enzymes / Renze Bais
  Basic Concepts
  Muscle Enzymes
  Liver Enzymes
  Pancreatic Enzymes
  Other Clinically Important Enzymes
  Enzymes as Cardiovascular Risk Markers
  Review Questions
  20. Tumor Markers and Cancer Genes / Daniel W. Chan
  Cancer
  Clinical Applications
  Evaluating Clinical Utility
  Clinical Guidelines
  Analytical Methods
  Enzymes
  Hormones
  Oncofetal Antigens
  Cytokeratins
  Carbohydrate Markers
  Blood Group Antigens
  Proteins
  Receptors
  Circulating Tumor
  Genetic and Molecular Markers
  Other Molecular Tests
  Microarray-Based Markers
  Review Questions
  21. Kidney Function Tests
  -Creatinine, Urea, and Uric Acid / Christopher P. Price
  Creatinine
  Urea
  Uric Acid
  Review Questions
  22. Carbohydrates / David B. Sacks
  Chemistry of Carbohydrates
  Biochemistry and Physiology
  Analytical Methodology
  Review Questions
  23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors / G. Russell Warnick
  Basic Lipids
  Lipoproteins
  Apolipoproteins
  Metabolism of Lipoproteins
  Clinical Significance
  Analysis of Lipids, Lipoproteins, and Apolipoproteins
  Advanced Testing for Risk of Cardiovascular Disease
  Review Questions
  24. Electrolytes and Blood Gases / Emily I. Schindler
  Electrolytes
  Principles of Osmotic Pressure and Osmosis
  Blood Gases and pH
  Review Questions
  25. Hormones / Michael Kleerekoper
  Classification
  Release and Action of Hormones
  Role of Hormone Receptors
  Postreceptor Actions of Hormones
  Measurements of Hormones and Related Ana-lytes
  Review Questions
  26. Catecholamines and Serotonin / Ronald J. Whitley
  Chemistry, Biosynthesis, Release, and Metabolism
  Physiology of Catecholamine and Serotonin Systems
  Clinical Applications
  Analytical Methodology
  Review Questions
  27. Vitamins, Trace Elements, and Nutritional Assessment / Norman B. Roberts
  Vitamins
  Trace Elements
  Review Questions
  28. Hemoglobin, Iron, and Bilirubin / Basil T. Doumas
  Hemoglobin
  Iron
  Bilirubin
  Review Questions
  29. Porphyrins and Porphyrias / George H. Elder
  Porphyrin and Heme Chemistry
  Primary Porphyrin Disorders
  Abnormalities of Porphyrin Metabolism not Caused by Porphyria
  Laboratory Diagnosis of Porphyria
  Analytical Methods
  Review Questions
  30. Therapeutic Drugs and Their Management / Gwendolyn A. McMillin
  Basic Concepts
  Clinical and Analytical Considerations
  Specific Drug Groups
  Review Questions
  31. Clinical Toxicology / Christopher P. Holstege
  Basic Information
  Screening Procedures for Detection of Drugs
  Pharmacology and Analysis of Specific Drugs and Toxic Agents
  Agents That Cause Cellular Hypoxia
  Alcohols
  Analgesics (Nonprescription)
  Agents Related to Anticholinergic Toxidrome
  Agents Related to Cholinergic Toxidrome
  Drugs of Abuse
  Drugs Used in Sexual Assault
  Review Questions
  32. Toxic Metals / Thomas P. Moyer
  Assessment of Metal Poisoning
  Specific Metals
  Review Questions
  pt. IV PATHOPHYSIOLOGY
  33. Diabetes / David B. Sacks
  Classification
  Hormones that Regulate Blood Glucose Concentration
  Measurement of Insulin, Proinsulin, C-Peptide, and Glucagon
  Pathogenesis of Type 1 Diabetes Mellitus
  Pathogenesis of Type 2 Diabetes Mellitus
  Diagnosis of Diabetes
  Chronic Complications of Diabetes Mellitus
  Role of the Clinical Laboratory in Diabetes Mellitus
  Self-Monitoring of Blood Glucose
  Alternatives to Meters for Monitoring of Blood
  Glucose
  Ketone Bodies
  Glycated Proteins
  Urinary Albumin Excretion
  Review Questions
  34. Cardiovascular Disease / Allan S. Jaffe
  Anatomy and Physiology of the Heart
  Cardiac Disease
  Cardiac Biomarkers
  Review Questions
  35. Kidney Disease / Edmund J. Lamb
  Anatomy
  Kidney Function
  Kidney Physiology
  Pathophysiology of Kidney Disease
  Other Diseases of the Kidney
  Renal Replacement Therapy
  Review Questions
  36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism / Mitchell G. Scott
  Total Body Water
  -Volume and Distribution
  Electrolytes
  Acid-Base Physiology
  Conditions Associated with Abnormal Acid-Base Status and Abnormal Electrolyte Composition of the Blood
  Review Questions
  37. Liver Disease / D. Robert Dufour
  Anatomy of the Liver
  Biochemical Functions of the Liver
  Clinical Manifestations of Liver Disease
  Diseases of the Liver
  Diagnostic Strategy
  Review Questions
  38. Gastrointestinal and Pancreatic Diseases / Peter G. Hill
  Anatomy
  Digestive Process
  Gastrointestinal Regulatory Peptides
  Stomach, Intestinal, and Pancreatic Diseases and Disorders-
  Review Questions
  39. Disorders of Bone and Mineral Metabolism / Leila Risteli
  Overview of Bone and Mineral Metabolism
  Contents note continued: Calcium
  Phosphate
  Magnesium
  Hormones Regulating Mineral Metabolism
  Integrated Control of Mineral Metabolism
  Biochemical Markers of Bone Turnover
  Metabolic Bone Diseases
  Review Questions
  40. Disorders of the Pituitary / Roger L. Bertholf
  Hypothalamic Regulation
  Hormones of the Adenohypophysis
  Hormones of the Neurohypophysis
  Assessment of Anterior Pituitary Lobe Reserve
  Review Questions
  41. Disorders of the Adrenal Cortex / William E. Winter
  General Steroid Chemistry
  Adrenocortical Steroids
  Dynamic Tests of Adrenal Function
  Disorders of the Adrenal Cortex
  Laboratory Evaluation of Adrenocortical Function
  Review Questions
  42. Thyroid Disorders / Roger L. Bertholf
  Thyroid Hormones
  Thyroid Disorders
  Analytical Methodology
  Review Questions
  43. Reproduction-Related Disorders / Ann M. Gronowski
  Male Reproductive Biology
  Female Reproductive Biology
  Infertility
  Analytical Methodology
  Review Questions
  44. Pregnancy and Prenatal Testing / Geralyn Lambert-Messerlian
  Human Pregnancy
  Maternal Adaptation
  Functional Development of the Fetus
  Maternal and Fetal Health Assessment
  Complications of Pregnancy
  Prenatal Screening for Fetal Defects
  Analytical Methodology
  Review Questions
  45. Newborn Screening and Inborn Errors of Metabolism / Nicola Longo
  Inheritance Pattern of Metabolic Disorders
  Newborn Screening
  Inborn Errors of Metabolism
  Diagnostic Tests for Inherited Disorders of Metabolism
  Review Questions
  46. Pharmacogenetics / Gwendolyn A. McMillin
  Defining Pharmacogenetic Targets
  Approaches to Pharmacogenetic Testing
  Clinical Applications of Pharmacogenetic Testing
  Drug Metabolism and Pharmacogenomics
  Review Questions
  pt. V MOLECULAR DIAGNOSTICS
  47. Principles of Molecular Biology / Rossa W. K. Chiu
  Landmark Developments in Genetics and Molecular Diagnostics
  Essentials
  Nucleic Acid Structure and Organization
  Nucleic Acid Physiology and Functional Regulation
  Genetics and Epigenetics
  Beyond the Nuclear Genome
  Understanding Our Genome
  Review Questions
  48. Nucleic Acid Techniques and Applications / Noriko Kusukawa
  Nucleic Acid Enzymes
  Amplification Techniques
  Detection Techniques
  Discrimination Techniques
  Review Questions
  49. Genomes and Nucleic Acid Variations / Noriko Kusukawa
  Genomes and Nucleic Acid Variations
  Review Questions
  pt. VI REFERENCE INFORMATION
  50. Reference Information for the Clinical Laboratory / David E. Bruns
  Reference Intervals and Values
  Therapeutic and Toxic Levels of Drugs.