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    Biocalculus : calculus, probability, and statistics for the life sciences / James Stewart, McMaster University and University of Toronto, Troy Day, Queen's University.

    • Title:Biocalculus : calculus, probability, and statistics for the life sciences / James Stewart, McMaster University and University of Toronto, Troy Day, Queen's University.
    •    
    • Author/Creator:Stewart, James, 1941- author.
    • Other Contributors/Collections:Day, Troy, 1968- author.
    • Published/Created:Boston, MA, USA : Cengage Learning, [2016]
    • Holdings

       
    • Library of Congress Subjects:Life sciences--Mathematics.
      Calculus.
    • Description:xlvii, 973 pages : illustrations (some color) ; 27 cm
    • Notes:Includes bibliographical references and indexes.
    • ISBN:1305114035 hardcover
      9781305114036 hardcover
    • Contents:Machine generated contents note: Case Study 1 Kill Curves and Antibiotic Effectiveness
      Case Study 2 Hosts, Parasites, and Time-Travel
      1.1. Four Ways to Represent a Function
      Representations of Functions
      Piecewise Defined Functions
      Symmetry
      Periodic Functions
      Increasing and Decreasing Functions
      1.2. Catalog of Essential Functions
      Linear Models
      Polynomials
      Power Functions
      Rational Functions
      Algebraic Functions
      Trigonometric Functions
      Exponential Functions
      Logarithmic Functions
      1.3. New Functions from Old Functions
      Transformations of Functions
      Combinations of Functions
      Project: The Biomechanics of Human Movement
      1.4. Exponential Functions
      Growth of Malarial Parasites
      Exponential Functions
      Exponential Growth
      HIV Density and Exponential Decay
      Number e
      1.5. Logarithms; Semilog and Log-Log Plots
      Inverse Functions
      Logarithmic Functions
      Natural Logarithms
      Graph and Growth of the Natural Logarithm
      Semilog Plots
      Log-Log Plots
      Project: The Coding Function of DNA
      1.6. Sequences and Difference Equations
      Recursive Sequences: Difference Equations
      Discrete-Time Models in the Life Sciences
      Project: Drug Resistance in Malaria
      Review
      Case Study 1a Kill Curves and Antibiotic Effectiveness
      2.1. Limits of Sequences
      Long-Term Behavior of a Sequence
      Definition of a Limit
      Limit Laws
      Geometric Sequences
      Recursion for Medication
      Geometric Series
      Logistic Sequence in the Long Run
      Project: Modeling the Dynamics of Viral Infections
      2.2. Limits of Functions at Infinity
      Monod Growth Function
      Definition of a Limit at Infinity
      Limits Involving Exponential Functions
      Infinite Limits at Infinity
      2.3. Limits of Functions at Finite Numbers
      Velocity Is a Limit
      Limits: Numerical and Graphical Methods
      One-Sided Limits
      Infinite Limits
      2.4. Limits: Algebraic Methods
      Limit Laws
      Additional Properties of Limits
      Limits of Trigonometric Functions
      2.5. Continuity
      Definition of a Continuous Function
      Which Functions Are Continuous?
      Approximating Discontinuous Functions by Continuous Ones
      Review
      Case Study 2a Hosts, Parasites, and Time-Travel
      3.1. Derivatives and Rates of Change
      Measuring the Rate of Increase of Blood Alcohol Concentration
      Tangent Lines
      Derivatives
      Rates of Change
      3.2. Derivative as a Function
      Graphing a Derivative from a Function's Graph
      Finding a Derivative from a Function's Formula
      Differentiability
      Higher Derivatives
      What a Derivative Tells Us about a Function
      3.3. Basic Differentiation Formulas
      Power Functions
      New Derivatives from Old
      Exponential Functions
      Sine and Cosine Functions
      3.4. Product and Quotient Rules
      Product Rule
      Quotient Rule
      Trigonometric Functions
      3.5. Chain Rule
      Combining the Chain Rule with Other Rules
      Exponential Functions with Arbitrary Bases
      Longer Chains
      Implicit Differentiation
      Related Rates
      How To Prove the Chain Rule
      3.6. Exponential Growth and Decay
      Population Growth
      Radioactive Decay
      Newton's Law of Cooling
      Project: Controlling Red Blood Cell Loss During Surgery
      3.7. Derivatives of the Logarithmic and Inverse Tangent Functions
      Differentiating Logarithmic Functions
      Logarithmic Differentiation
      Number e as a Limit
      Differentiating the Inverse Tangent Function
      3.8. Linear Approximations and Taylor Polynomials
      Tangent Line Approximations
      Newton's Method
      Taylor Polynomials
      Project: Harvesting Renewable Resources
      Review
      Case Study 1b Kill Curves and Antibiotic Effectiveness
      4.1. Maximum and Minimum Values
      Absolute and Local Extreme Values
      Fermat's Theorem
      Closed Interval Method
      Project: The Calculus of Rainbows
      4.2. How Derivatives Affect the Shape of a Graph
      Mean Value Theorem
      Increasing and Decreasing Functions
      Concavity
      Graphing with Technology
      4.3. L'Hospital's Rule: Comparing Rates of Growth
      Indeterminate Quotients
      Which Functions Grow Fastest?
      Indeterminate Products
      Indeterminate Differences
      Project: Mutation-Selection Balance in Genetic Diseases
      4.4. Optimization Problems
      Project: Flapping and Gliding
      Project: The Tragedy of the Commons: An Introduction to Game Theory
      4.5. Recursions: Equilibria and Stability
      Equilibria
      Cobwebbing
      Stability Criterion
      4.6. Antiderivatives
      Review
      5.1. Areas, Distances, and Pathogenesis
      Area Problem
      Distance Problem
      Pathogenesis
      5.2. Definite Integral
      Calculating Integrals
      Midpoint Rule
      Properties of the Definite Integral
      5.3. Fundamental Theorem of Calculus
      Evaluating Definite Integrals
      Indefinite Integrals
      Net Change Theorem
      Fundamental Theorem
      Differentiation and Integration as Inverse Processes
      Project: The Outbreak Size of an Infectious Disease
      5.4. Substitution Rule
      Substitution in Indefinite Integrals
      Substitution in Definite Integrals
      Symmetry
      5.5. Integration by Parts
      Indefinite Integrals
      Definite Integrals
      5.6. Partial Fractions
      5.7. Integration Using Tables and Computer Algebra Systems
      Tables of Integrals
      Computer Algebra Systems
      Can We Integrate All Continuous Functions?
      5.8. Improper Integrals
      Review
      Case Study 1c Kill Curves and Antibiotic Effectiveness
      6.1. Areas Between Curves
      Cerebral Blood Flow
      Project: Disease Progression and Immunity
      Project: The Gini Index
      6.2. Average Values
      6.3. Further Applications to Biology
      Survival and Renewal
      Blood Flow
      Cardiac Output
      6.4. Volumes
      Review
      Case Study 1d Kill Curves and Antibiotic Effectiveness
      Case Study 2b Hosts, Parasites, and Time-Travel
      7.1. Modeling with Differential Equations
      Models of Population Growth
      Classifying Differential Equations
      Project: Chaotic Blowflies and the Dynamics of Populations
      7.2. Phase Plots, Equilibria, and Stability
      Phase Plots
      Equilibria and Stability
      Mathematical Derivation of the Local Stability Criterion
      Project: Catastrophic Population Collapse: An Introduction to Bifurcation Theory
      7.3. Direction Fields and Euler's Method
      Direction Fields
      Euler's Method
      7.4. Separable Equations
      Project: Why Does Urea Concentration Rebound after Dialysis?
      7.5. Systems of Differential Equations
      Parametric Curves
      Systems of Two Autonomous Differential Equations
      Project: The Flight Path of Hunting Raptors
      7.6. Phase Plane Analysis
      Equilibria
      Qualitative Dynamics in the Phase Plane
      Project: Determining the Critical Vaccination Coverage
      Review
      Case Study 2c Hosts, Parasites, and Time-Travel
      8.1. Coordinate Systems
      Three-Dimensional Space
      Higher-Dimensional Space
      8.2. Vectors
      Combining Vectors
      Components
      8.3. Dot Product
      Projections
      Project: Microarray Analysis of Genome Expression
      Project: Vaccine Escape
      8.4. Matrix Algebra
      Matrix Notation
      Matrix Addition and Scalar Multiplication
      Matrix Multiplication
      8.5. Matrices and the Dynamics of Vectors
      Systems of Difference Equations: Matrix Models
      Leslie Matrices
      Summary
      8.6. Inverse and Determinant of a Matrix
      Inverse of a Matrix
      Determinant of a Matrix
      Solving Systems of Linear Equations
      Project: Cubic Splines
      8.7. Eigenvectors and Eigenvalues
      Characterizing How Matrix Multiplication Changes Vectors
      Eigenvectors and Eigenvalues
      8.8. Iterated Matrix Models
      Solving Matrix Models
      Solutions with Complex Eigenvalues
      Perron-Frobenius Theory
      Project: The Emergence of Geometric Order in Proliferating Cells
      Review
      9.1. Functions of Several Variables
      Functions of Two Variables
      Graphs
      Level Curves
      Functions of Three Variables
      Limits and Continuity
      9.2. Partial Derivatives
      Interpretations of Partial Derivatives
      Functions of More Than Two Variables
      Higher Derivatives
      Partial Differential Equations
      9.3. Tangent Planes and Linear Approximations
      Tangent Planes
      Linear Approximations
      Project: The Speedo LZR Racer
      9.4. Chain Rule
      Implicit Differentiation
      9.5. Directional Derivatives and the Gradient Vector
      Directional Derivatives
      Gradient Vector
      Maximizing the Directional Derivative
      9.6. Maximum and Minimum Values
      Absolute Maximum and Minimum Values
      Review
      10.1. Qualitative Analysis of Linear Systems
      Terminology
      Saddles
      Nodes
      Spirals
      10.2. Solving Systems of Linear Differential Equations
      General Solution
      Nullclines versus Eigenvectors
      Saddles
      Nodes
      Spirals
      Long-Term Behavior
      10.3. Applications
      Metapopulations
      Natural Killer Cells and Immunity
      Gene Regulation
      Transport of Environmental Pollutants
      Project: Pharmacokinetics of Antimicrobial Dosing
      10.4. Systems of Nonlinear Differential Equations
      Linear and Nonlinear Differential Equations
      Local Stability Analyses
      Linearization
      Examples
      Review
      Case Study 2d: Hosts, Parasites, and Time-Travel
      11.1. Numerical Descriptions of Data
      Types of Variables
      Categorical Data
      Numerical Data: Measures of Central Tendency
      Numerical Data: Measures of Spread
      Numerical Data: The Five-Number Summary
      Outliers
      11.2. Graphical Descriptions of Data
      Contents note continued: Displaying Categorical Data
      Displaying Numerical Data: Histograms
      Interpreting Area in Histograms
      Normal Curve
      11.3. Relationships between Variables
      Two Categorical Variables
      Categorical and Numerical Variables
      Two Numerical Variables
      11.4. Populations, Samples, and Inference
      Populations and Samples
      Properties of Samples
      Types of Data
      Causation
      Project: The Birth Weight Paradox
      Review
      12.1. Principles of Counting
      Permutations
      Combinations
      12.2. What Is Probability?
      Experiments, Trials, Outcomes, and Events
      Probability When Outcomes Are Equally Likely
      Probability in General
      12.3. Conditional Probability
      Conditional Probability
      Multiplication Rule and Independence
      Law of Total Probability
      Bayes' Rule
      Project: Testing for Rare Diseases
      12.4. Discrete Random Variables
      Describing Discrete Random Variables
      Mean and Variance of Discrete Random Variables
      Bernoulli Random Variables
      Binomial Random Variables
      Project: DNA Supercoiling
      Project: The Probability of an Avian Influenza Pandemic in Humans
      12.5. Continuous Random Variables
      Describing Continuous Random Variables
      Mean and Variance of Continuous Random Variables
      Exponential Random Variables
      Normal Random Variables
      Review
      13.1. Sampling Distribution
      Sums of Random Variables
      Sampling Distribution of the Mean
      Sampling Distribution of the Standard Deviation
      13.2. Confidence Intervals
      Interval Estimates
      Student's t-Distribution
      13.3. Hypothesis Testing
      Null and Alternative Hypotheses
      t-Statistic
      P-Value
      Summary
      13.4. Contingency Table Analysis
      Hypothesis Testing with Contingency Tables
      Chi-Squared Test Statistic
      Hypothesis Test
      Summary
      Review
      A. Intervals, Inequalities, and Absolute Values
      B. Coordinate Geometry
      C. Trigonometry
      D. Precise Definitions of Limits
      E. Few Proofs
      F. Sigma Notation
      G. Complex Numbers
      H. Statistical Tables.
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