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    Peroxynitrite detection in biological media : challenges and advances / Edited by Serban F. Peteu, Sabine Szunerits and Mekki Bayachou.

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    • Title:Peroxynitrite detection in biological media : challenges and advances / Edited by Serban F. Peteu, Sabine Szunerits and Mekki Bayachou.
    •    
    • Other Contributors/Collections:Peteu, Serban F., editor.
      Szunerits, Sabine, editor.
      Bayachou, Mekki, editor.
      Royal Society of Chemistry (Great Britain), issuing body.
    • Published/Created:Cambridge : Royal Society Of Chemistry, [2016]

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    • Library of Congress Subjects:Nitric oxide.
      Biosensors.
    • Medical Subjects: Nitric Oxide--physiology.
      Biosensing Techniques--methods.
    • Description:xviii, 232 pages : illustrations (some color) ; 24 cm
    • Series:RSC detection science series.
    • Notes:Includes bibliographical references and index.
    • ISBN:9781782620853 hardcover
      1782620850 hardcover
    • Contents:Machine generated contents note: 1.1. History / Willem H. Koppenol
      1.1.1. Before 1990 / Willem H. Koppenol
      1.1.2. 1990 and Later / Willem H. Koppenol
      1.2. Peroxynitrite In Vivo / Willem H. Koppenol
      1.3. Challenges to the Detection of Peroxynitrite / Willem H. Koppenol
      1.4. Nomenclature / Willem H. Koppenol
      Acknowledgements / Willem H. Koppenol
      References / Willem H. Koppenol
      2.1. General Remarks on the Concept of "Redox Signaling" / Sabine Borgmann
      2.2. Basic Chemical Properties of Peroxynitrite Compared with Other RNS/ROS as Signaling Molecules / Sabine Borgmann
      2.3. Complex Interplay of Peroxynitrite and Other RNS/ROS in Biological Systems / Sabine Borgmann
      2.4. Implications of Selecting a Model System for In Vitro, In Vivo and Ex Vivo Experiments / Sabine Borgmann
      2.4.1. Use of Biological Sample Materials / Sabine Borgmann
      2.4.2. Performing Cell Culture Studies / Sabine Borgmann
      2.4.3. Use of Scavengers, Pharmaceuticals or Enzymes to Alter Peroxynitrite Signaling Pathways / Sabine Borgmann
      2.5. General Challenges of Detecting RNS and ROS: The Complexity of the Task to Quantify Peroxynitrite in Biological Samples / Sabine Borgmann
      2.5.1. Overview of the Different Quantification Approaches / Sabine Borgmann
      2.5.2. Parameters Impacting the Performance of ON00- Quantification / Sabine Borgmann
      2.6. Conclusions / Sabine Borgmann
      Acknowledgements / Sabine Borgmann
      References / Sabine Borgmann
      3.1. Background / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.2. Overview of Major Methods of Peroxynitrite Synthesis / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.2.1. Peroxynitrite from the Reaction of Nitrite with Acidified Hydrogen Peroxide / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.2.2. Synthesis of Peroxynitrite in a Two-Phase System Using Isoamyl Nitrite and H2O2 / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.2.3. Reaction of H2O2 and Water Soluble Nitrites such as 2-Ethoxyethyl Nitrite in Basic Medium / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.2.4. Reaction of Ozone with Azide Ions in the Presence of a Low Concentration of Alkali / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.2.5. Other Methods of Peroxynitrite Synthesis / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.2.6. Generation of Peroxynitrite from 3-(4-Morpholinyl) Sydnonimine Hydrochloride / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.3. Advantages and Limitations of the Various Peroxynitrite Synthesis Routes / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.3.1. Characterization of Peroxynitrite Sensors and Evaluation of Performance: Are Buffers Indifferent? / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      3.3.2. Advantages and Limitations of the Various Methods of Peroxynitrite Synthesis and Generation for Sensing Purposes / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      References / Mekki Bayachou / Ghaith Altawallbeh / Haitham Kalil / Sarah Wojciechowski / Tiyash Bose
      4.1. Introduction: Challenges for the Formation of Selective and Sensitive Matrices for Peroxynitrite Detection / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      4.2. Polymeric Films / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      4.2.1. Metallophthalocyanine films (MPCs) / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      4.2.2. Porphyrins / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      4.2.3. Conducting Polymers / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      4.3. Graphene-Based Matrices / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      4.4. Conclusion and Perspectives / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      Acknowledgements / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      References / Sabine Szunerits / Serban Peteu / Rabah Boukherroub
      5.1. Challenges in the Detection of Peroxynitrite in Biological Conditions / Sophie Griveau / Fethi Bedioui
      5.2. Challenges in the Preparation and Storage of PON / Sophie Griveau / Fethi Bedioui
      5.3. Main Electrochemical Approaches for the Detection of PON in Biological Solutions / Sophie Griveau / Fethi Bedioui
      5.3.1. Electrochemical Strategies for the Detection of PON / Sophie Griveau / Fethi Bedioui
      5.3.2. Significant Examples of In Vivo Electrochemical Sensing of PON / Sophie Griveau / Fethi Bedioui
      5.4. Conclusion and Perspectives in the Detection of PON and Related Species / Sophie Griveau / Fethi Bedioui
      References / Sophie Griveau / Fethi Bedioui
      6.1. Introduction / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.2. Electrochemical Detection Using C-Pt UMEs / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.2.1. "Artificial Synapse" Configuration / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.2.2. Identification of Peroxynitrite Among the ROS/RNS Detected on Single Cells with C-Pt Fiber UME / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.2.3. Implications of Peroxynitrite in Numerous Biological Mechanisms as Detected by Electrochemistry / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.3. Analytical Evolution of Electrochemical Detection / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.3.1. Adapted Protocols from the "Artificial Synapse" Configuration / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.3.2. Other Examples / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      6.4. Conclusion / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      References / Christian Amatore / Manon Guille-Collignon / Frédéric Lemaitre
      7.1. Introduction / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.2. Electrophoresis / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.2.1. CE / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.2.2. ME / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.3. Detection Strategies / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.3.1. UV Absorbance / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.3.2. Amperometric Detection / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.3.3. Conductivity Detection / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.4. Electrophoretic Separation and Direct Detection of Peroxynitrite / Joseph M. Siegel / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte
      7.4.1. CE-UV / José A.F. da Silva / Dulan B. Gunasekara / Richard P.S. DE Campos / Joseph M. Siegel / Susan M. Lunte
      7.4.2. ME-EC / Richard P.S. DE Campos / Dulan B. Gunasekara / José A.F. da Silva / Susan M. Lunte / Joseph M. Siegel
      7.5. Indirect Detection of Peroxynitrite by Electrophoretic Methods / José A.F. da Silva / Susan M. Lunte / Dulan B. Gunasekara / Richard P.S. DE Campos / Joseph M. Siegel
      7.5.1. ME-EC/C4D / Susan M. Lunte / José A.F. da Silva / Dulan B. Gunasekara / Richard P.S. DE Campos / Joseph M. Siegel
      7.5.2. Monitoring Peroxynitrite Through its Reaction Products with Biomolecules / José A.F. da Silva / Susan M. Lunte / Dulan B. Gunasekara / Richard P.S. DE Campos / Joseph M. Siegel
      7.6. Future Directions / Susan M. Lunte / José A.F. da Silva / Dulan B. Gunasekara / Richard P.S. DE Campos / Joseph M. Siegel
      Acknowledgements / José A.F. da Silva / Susan M. Lunte / Dulan B. Gunasekara / Richard P.S. DE Campos / Joseph M. Siegel
      References / José A.F. da Silva / Dulan B. Gunasekara / Richard P.S. DE Campos / Joseph M. Siegel / Susan M. Lunte
      8.1. Introduction / Ying Liu / Serban F. Peteu / R. Mark Worden
      8.2. Molecular Mechanisms of the Interaction of PON with Biomembrane Lipids / Ying Liu / Serban F. Peteu / R. Mark Worden
      8.3. Effects of PON on Biomembrane Properties / Ying Liu / Serban F. Peteu / R. Mark Worden
      8.4. Electrochemical Methods to Measure the Effects of PON on Biomembrane Lipids / Ying Liu / Serban F. Peteu / R. Mark Worden
      8.4.1. Planar Bilayer Methods / Ying Liu / Serban F. Peteu / R. Mark Worden
      8.4.2. Tethered Bilayer Methods / Serban F. Peteu / R. Mark Worden / Ying Liu
      8.5. Optical Methods to Measure PON Effects on Biomembrane Lipids / Serban F. Peteu / Ying Liu / R. Mark Worden
      8.6. Example of the Measurement of PON Effects Using a Tethered Biomimetic Interface / Serban F. Peteu / Ying Liu / R. Mark Worden
      8.7. Conclusions / Serban F. Peteu / R. Mark Worden / Ying Liu
      References / Ying Liu / Serban F. Peteu / R. Mark Worden
      Contents note continued: 9.1. Introduction / Laurentiu Rusen / Alina Vasilescu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu / Ioana S. Hosu / Valentina Dinca / Mihaela Filipescu
      9.2. Approaches to Enhance the Selectivity of PON Detection / Laurentiu Rusen / Alina Vasilescu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu / Ioana S. Hosu / Valentina Dinca / Mihaela Filipescu
      9.2.1. Selectivity via Chemical Resolution / Laurentiu Rusen / Alina Vasilescu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu / Ioana S. Hosu / Valentina Dinca / Mihaela Filipescu
      9.2.2. Selectivity via Chemical Sensitivity / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Alina Vasilescu / Serban F. Peteu / Mihaela Filipescu / Valentina Dinca / Maria Dinescu
      9.2.3. Selectivity via Detection Method / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu
      9.2.4. Selectivity via Permeable Membranes / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu
      9.2.5. Selectivity via Deposition Technique / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu
      9.3. Selective PON Detection with Simultaneous Detection of Interfering Species / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu
      9.4. Confirming the Identity of the PON Electrochemical Signal / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu
      9.5. Conclusions / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu
      Acknowledgements / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu
      References / Alina Vasilescu / Valentina Dinca / Mihaela Filipescu / Laurentiu Rusen / Ioana S. Hosu / Rabah Boukherroub / Sabine Szunerits / Maria Dinescu / Serban F. Peteu
      10.1. Introduction to Peroxynitrite / Zhijie Chen / Tan M. Truong / Hui-wang Ai
      10.1.1. Production of Peroxynitrite in Biological Systems / Zhijie Chen / Tan M. Truong / Hui-wang Ai
      10.1.2. Biological Chemistry of Peroxynitrite / Tan M. Truong / Hui-wang Ai / Zhijie Chen
      10.1.3. Peroxynitrite-Induced Cytotoxicity / Hui-wang Ai / Tan M. Truong / Zhijie Chen
      10.2. Principles of Fluorescence and Fluorescent Probes / Tan M. Truong / Hui-wang Ai / Zhijie Chen
      10.2.1. Phenomenon of Fluorescence / Tan M. Truong / Hui-wang Ai / Zhijie Chen
      10.2.2. Applications of Fluorescence Technology / Tan M. Truong / Hui-wang Ai / Zhijie Chen
      10.2.3. Fluorescent Probes / Hui-wang Ai / Zhijie Chen / Tan M. Truong
      10.3. Development of Fluorescent Probes for Peroxynitrite / Hui-wang Ai / Zhijie Chen / Tan M. Truong
      10.3.1. Oxidation-Based Probes / Tan M. Truong / Hui-wang Ai / Zhijie Chen
      10.3.2. Nitration-Based Probes / Tan M. Truong / Hui-wang Ai / Zhijie Chen
      10.4. Conclusions and Future Perspectives / Hui-wang Ai / Zhijie Chen / Tan M. Truong
      References / Hui-wang Ai / Zhijie Chen / Tan M. Truong
      11.1. Introduction / Peng Li / Keli Han
      11.2. Design of the Probes / Keli Han / Peng Li
      11.3. Synthesis, Characterization and Spectroscopic Evaluation of the Probes / Keli Han / Peng Li
      11.4. Fluorescence Imaging of PN in Living Cells and Animals / Peng Li / Keli Han
      11.5. Conclusions and Perspectives / Keli Han / Peng Li
      References / Keli Han / Peng Li.
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