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    Antiresorptive drug-related osteonecrosis of the jaw (ARONJ) : a guide to research / [edited by] Kenneth E. Fleisher, Risto Kontio, Sven Otto.

    • Title:Antiresorptive drug-related osteonecrosis of the jaw (ARONJ) : a guide to research / [edited by] Kenneth E. Fleisher, Risto Kontio, Sven Otto.
    •    
    • Other Contributors/Collections:Fleisher, Kenneth E., editor.
      Kontio, Risto, editor.
      Otto, Sven, 1978- editor.
    • Published/Created:Dubendorf, Switzerland : AO Foundation, [2016]
      Stuttgart, Germany ; New York, NY : Distribution by Georg Thieme Verlag,
    • Holdings

       
    • Library of Congress Subjects:Jaws--Necrosis.
      Osteoporosis--Chemotherapy--Complications.
    • Medical Subjects: Bisphosphonate-Associated Osteonecrosis of the Jaw.
    • Description:viii, 64 pages ; 28 cm
    • Notes:Includes bibliographical references.
    • ISBN:3132412708 paperback
      9783132412705 paperback
    • Contents:Machine generated contents note: 1. Definition, nomenclature, and classification of antiresorptive drug-related osteonecrosis of the jaw (ARONJ) / Tae-Geon Kwon
      When was bone necrosis first reported and how is it defined?
      What definitions for antiresorptive drug-related osteonecrosis of the jaw (ARONJ) exist?
      Why are different terms used and why are there so many?
      How is ARONJ classified?
      2. Clinical features of antiresorptive drug-related osteonecrosis of the jaw / Bente Brokstad Herlofson
      How do we take a medical history based on relevant factors?
      How do we diagnose and classify nonexposed osteonecrosis?
      How do we avoid misdiagnosing common dental infections like apical periodontal processes as nonexposed antiresorptive drug-related osteonecrosis of the jaw (ARONJ)?
      Is the development of ARONJ spontaneous or caused by a preceding trauma or dental procedure?
      What is the difference between ARONJ, osteomyelitis (OM), and osteoradionecrosis (ORN)?
      3. Imaging modalities for antiresorptive drug-related osteonecrosis of the jaw / Niloufar Amintavakoli
      Which imaging modalities are used for the diagnosis of antiresorptive drug-related osteonecrosis of the jaw (ARONJ)?
      What are the advantages and disadvantages of each imaging modality?
      What are the radiographic findings for ARONJ?
      What is meant by metabolic changes for ARONJ lesions?
      4. Treatment and outcomes measures for antiresorptive drug-related osteonecrosis of the jaw / Stefano Fedele
      What are the real aims of treatment for antiresorptive drug-related osteonecrosis of the jaw (ARONJ)?
      What are relevant outcomes measures for the treatment of ARONJ?
      What is the impact of definition and staging for ARONJ?
      What therapeutic strategies exist for ARONJ?
      5. Risk factors for antiresorptive drug-related osteonecrosis of the jaw / Robert E Marx
      What are the real risk factors for antiresorptive drug-related osteonecrosis of the jaw (ARONJ)?
      What are the initiation factors for ARONJ?
      Where are the vulnerable sites?
      What are the relevant comorbidities?
      6. Pathogenesis of antiresorptive drug-related osteonecrosis of the jaw / Sven Otto
      Which theories exist for the pathogenesis of antiresorptive drug-related osteonecrosis of the jaw (ARONJ)?
      Why are the jaw bones predominantly affected?
      Why can nitrogen-containing bisphosphonates and denosumab cause ARONJ?
      7. Small animal models for antiresorptive drug-related osteonecrosis of the jaw / Stephan Zeiter
      Does small animal investigation make sense?
      What are the opportunities and limitations of small animal investigation?
      What are the advantages and disadvantages of small animal models of antiresorptive drug-related osteonecrosis of the jaw (ARONJ)?
      What controversies exist concerning these small animal models?
      Are there significant differences among the various small animal models of ARONJ?
      Does jaw size matter?
      8. Large animal models for antiresorptive drug-related osteonecrosis of the jaw / Christoph Pautke
      Can antiresorptive drug-related osteonecrosis of the jaw (ARONJ) be related in large animals?
      Are animal models really necessary?.
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