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• Title:[Applied therapeutics for clinical pharmacists.]
  Applied therapeutics : the clinical use of drugs / [edited by] Caroline S. Zeind, Michael G. Carvalho.
  
•    
• Other Contributors/Collections:Zeind, Caroline S., editor.
  Carvalho, Michael G., editor.
  
• Published/Created:Philadelphia : Wolters Kluwer, [2018]
  

• Holdings

  Holdings Record Display

  • Location:BMB LIBRARY (VGH) stacksWhere is this?
    
  • Call Number: WB330 .A651 2018
    
  • Number of Items:1
    
  • Status:Available
    

  • Location:OKANAGAN LIBRARY stacksWhere is this?
    
  • Call Number: WB330 .A651 2018
    
  • Number of Items:1
    
  • Status:Available
    

  • Location: c.1  Temporarily shelved at WOODWARD LIBRARY reserve collectionWhere is this?
    
  • Call Number: WB330 .A651 2018
    
  • Number of Items:1
    
  • Status:Available
    

   
• Library of Congress Subjects:Chemotherapy.
  Pharmacology.
  Chemotherapy--Handbooks, manuals, etc.
  
• Medical Subjects: Drug Therapy.
  
• Genre/Form:Handbooks and manuals.
  
• Edition:Eleventh edition.
  
• Description:xxxvi, 2, 374 pages : illustrations ; 29 cm
  
• Summary:This text uses a case-based approach to help students master the fundamentals of drug therapeutics. Students will learn the basics of common diseases and disorders and develop practical problem-solving skills for devising and implementing successful drug treatment regimens. Case studies integrated into each chapter illustrate key concepts and principles of therapeutics and give students practice in developing their own evidence-based therapeutic plans.
  
• Notes:Includes bibliographical references and indexes.
  
• ISBN:9781496318299 hardcover
  1496318293 hardcover
  9781496353795
  149635379X
  
• Contents:Machine generated contents note: SECTION 1 GENERAL PRINCIPLES / Maria D. Kostka-Rokosz
  1. Medication Therapy Management and Assessment of Therapy / Joseph W. Ferullo
  Sources of Patient Information
  Effective Communication and the Patient Interview
  Obtaining a Patient History
  Approach to and Assessment of Patient Therapy
  Medication Therapy Management Services in the Community Pharmacy or Ambulatory Setting
  Medication Therapy Management in the Acute Care Setting
  Medication Therapy Management and Pharmacogenomics
  Conclusion
  Acknowledgment
  Key References and Websites
  2. Interpretation of Clinical Laboratory Tests / Stefanie C. Nigro
  General Principles
  Fluids and Electrolytes
  Multichemistry Panels
  Proteins
  Cardiac Markers
  Liver Function Tests
  Miscellaneous Tests
  Hematology
  Urinalysis
  Therapeutic Drug Monitoring
  Patient-Directed Monitoring and Testing
  Key References and Websites
  3. Drug Interactions / Michael G. Carvalho
  Definition
  Risk Factors for Drug Interactions
  Mechanisms of Drug Interactions
  Management of Drug Interactions
  Resources and Evidence for Clinical Decision Support
  Conclusion
  Key References and Websites
  4. Pharmacogenomics and Personalized Medicine / Jonathan D. Picker
  Pharmacokinetic Implications
  Pharmacodynamic Implications
  Toxicity Implications
  Drug Target Implications
  Nonmetabolism Implications
  Peculiarities of CYP2D6
  Developmental Impact and Pharmacogenomics
  Family Implications of Pharmacogenetics
  Making the Case for Pharmacogenetics
  Conclusion
  Key References and Websites
  5. Managing Drug Overdoses and Poisonings / Sara Zhou
  General Management
  Assessment of Salicylate Ingestion
  Assessment of Iron Ingestion
  Assessment of Central Nervous System Depressant Versus Antidepressant Ingestion
  Assessment of Acetaminophen Ingestion
  Conclusion
  Key References and Websites
  6. End-of-Life Care / Victoria F. Ferraresi
  Hospice and Palliative Care
  Symptom Management
  Key References and Websites
  7. Interprofessional Education and Practice / Beth Buyea
  Core IPE Competencies
  IPE Terminology
  Incorporating IPE in the Curriculum
  IPE Models
  Potential Barriers to IPE
  Future of IPE
  Conclusion
  Key References and Websites
  SECTION 2 CARDIAC AND VASCULAR DISORDERS / Judy W. Cheng
  8. Dyslipidemias, Atherosclerosis, and Coronary Heart Disease / Pamela B. Morris
  Lipid Metabolism
  Abnormalities in Lipid Metabolism
  Lipoproteins and ASCVD Risk
  Clinical Evaluation and Management of ASCVD Risk
  Pharmacologic Therapy
  Key References
  9. Essential Hypertension / Judy W. Cheng
  Introduction
  Clinical Evaluation
  Principles of Treatment
  Hypertension Management
  Clinical Scenarios
  Key References and Websites
  10. Peripheral Vascular Disorders / Mary G. Amato
  Peripheral Arterial Disease
  Raynaud Phenomenon
  Nocturnal Leg Muscle Cramps
  Key References and Websites
  11. Thrombosis / Erika L. Hellenbart
  General Principles
  Deep Vein Thrombosis
  Pulmonary Embolism
  Prevention of Cardiogenic Thromboembolism
  Bridge Therapy
  Drug Interactions
  Key References and Websites
  12. Chronic Stable Angina / Toby C. Trujillo
  Chronic Stable Angina
  Overview of Drug and Nondrug Therapy
  Clinical Presentation of Chronic Stable Angina
  Revascularization
  Variant Angina (Coronary Artery Spasm)
  Cardiac Syndrome X
  Key References and Websites
  13. Acute Coronary Syndrome / Robert L. Page
  Acute Coronary Disease
  Overview of Drug and Nondrug Therapy
  Clinical Presentation of ACS
  Treatment for ST Segment Elevation Myocardial Infarction
  Treatment for Unstable Angina or Non-ST Segment Elevation Myocardial Infarction
  Long-Term Therapy
  Lifestyle Modifications
  Summary
  Key References and Websites
  14. Heart Failure / Joel C. Marrs
  Patient Evaluation
  Treatment
  Heart Failure with Preserved Ejection Fraction
  Key References and Websites
  15. Cardiac Arrhythmias / James S. Kalus
  Electrophysiology
  Supraventricular Arrhythmias
  Conduction Blocks
  Ventricular Arrhythmias
  Cardiopulmonary Arrest
  Key References and Websites
  16. Hypertensive Crises / Sandeep Devabhakthuni
  Clinical Presentation of Hypertensive Urgency
  Clinical Presentation of Hypertensive Emergency
  Overview of Treatment
  Hypertensive Urgencies
  Hypertensive Emergencies
  Key References and Websites
  17. Shock / Jason S. Haney
  Introduction
  Causes
  Pathophysiology
  Clinical Presentation and Diagnosis
  Treatment Overview
  Hemodynamic Monitoring
  Etiologic Classification of Shock and Common Mechanisms
  Hypovolemic Shock
  Cardiogenic Shock
  Septic Shock
  Disseminated Intravascular Coagulation
  Key References and Websites
  SECTION 3 PULMONARY DISORDERS / Kathy Zaiken
  18. Asthma / Christopher K. Finch
  Asthma
  Acute Asthma
  Chronic Asthma
  Exercise-Induced Asthma
  Patient Education
  Nocturnal Asthma
  Drug-Induced Asthma
  Outcomes
  Complementary Alternative Therapies
  Key References and Websites
  19. Chronic Obstructive Pulmonary Disease / Kathy Zaiken
  Diagnosis and Patient Assessment
  General Management Considerations
  Pharmacotherapy
  Pharmacologic Therapy by Disease Severity
  COPD Exacerbation
  COPD Group A (Low Risk; Less Symptoms)
  COPD Group B (Low Risk; More Symptoms) With Disease Progression
  COPD Group C (High Risk; Less Symptoms)
  Key References and Websites
  20. Acute and Chronic Rhinitis / Dennis M. Williams
  Definition
  Causes and Classifications
  Epidemiology and Impact
  Anatomy and Physiology
  Etiology of Allergic Rhinitis
  Pathophysiology
  Clinical Presentation and Assessment of Rhinitis
  Overview of Treatment
  Specific Therapeutic Options
  Drug-Induced Nasal Congestion: Rhinitis Medicamentosa
  Idiopathic Rhinitis
  Mixed Allergic-Nonallergic Rhinitis
  Summary
  Key References and Websites
  21. Cystic Fibrosis / Michelle Condren
  Genetic Basis
  Clinical Manifestations
  Diagnosis
  Early Interventions and Therapy
  Lung Transplantation
  Key References and Websites
  SECTION 4 GASTROINTESTINAL DISORDERS / Carrie A. Sincak
  22. Nausea and Vomiting / Joseph Todd Carter
  Definition
  Epidemiology and Clinical Presentation
  Pathophysiology
  Diagnosis
  Motion Sickness
  Chemotherapy-Induced Nausea and Vomiting
  Radiation-Induced Nausea and Vomiting
  Postoperative Nausea and Vomiting
  Key References and Websites
  23. Upper Gastrointestinal Disorders / Jeffrey J. Fong
  Upper Gastrointestinal Disorders
  Physiology of the Upper Gastrointestinal Tract
  Pharmacotherapy of Drugs Used to Treat Acid-Related Disorders
  Dyspepsia
  Peptic Ulcer Disease
  Helicobacter Pylori-Related Peptic Ulcer
  Nonsteroidal Anti-Inflammatory Drug-Induced Peptic Ulcer
  Zollinger-Ellison Syndrome
  Gastroesophageal Reflux Disease
  Upper Gastrointestinal Bleeding
  Key References and Websites
  24. Lower Gastrointestinal Disorders / Charmaine Rochester-Eyeguokan
  Overview of Inflammatory Bowel Disease
  Ulcerative Colitis
  Crohn's Disease
  Irritable Bowel Syndrome
  Key References and Websites
  25. Complications of End-Stage Liver Disease / Mary F. Hebert
  Overview
  Pathogenesis of Cirrhosis
  Complications of Cirrhosis
  Ascites
  Esophageal Varices
  Hepatic Encephalopathy
  Hepatorenal Syndrome
  Key References and Websites
  SECTION 5 RENAL DISORDERS / Myrna Y. Munar
  26. Acid-Base Disorders / Luis S. Gonzalez
  Acid-Base Physiology
  Evaluation of Acid-Base Disorders
  Metabolic Acidosis
  Metabolic Alkalosis
  Respiratory Acidosis
  Respiratory Alkalosis
  Mixed Acid
  Base Disorders
  Key References and Websites
  27. Fluid and Electrolyte Disorders / Priscilla P. How
  Basic Principles
  Disorders in Volume Regulation
  Disorders in Osmoregulation
  Clinical Use of Diuretics
  Potassium
  Calcium
  Phosphorus
  Magnesium
  Key References and Websites
  28. Chronic Kidney Disease / Darius L. Mason
  Introduction
  End-Stage Renal Disease (Chronic Kidney Disease 5D)
  Diabetic Nephropathy
  Fluid and Electrolyte Complications
  Anemia of Chronic Kidney Disease
  Cardiovascular Complications
  Mineral and Bone Disorders
  Other Complications of CKD
  Glomerular Disease
  Key References and Websites
  29. Acute Kidney Injury / Oussayma Moukhachen
  Definition
  Epidemiology
  Prognosis
  Clinical Course
  Pathogenesis
  Clinical Evaluation
  Prerenal and Functional Acute Kidney Injury
  Intrinsic Acute Kidney Injury
  Tubulointerstitial Diseases
  Postrenal Acute Kidney Injury
  Supportive Management of Acute Kidney Injury
  Key References and Websites
  30. Renal Dialysis / Myrna Y. Munar
  Hemodialysis
  Peritoneal Dialysis
  Key References and Websites
  31. Dosing of Drugs in Renal Failure / David J. Quan
  Basic Principles
  Pharmacokinetics and Pharmacodynamics of Specific Drugs in Renal Failure
  Effect of Renal Failure on Metabolized Drugs
  Assessing Renal Function in the Elderly
  Summary
  Key References and Websites
  SECTION 6 IMMUNOLOGIC DISORDERS / Steven Gabardi
  Contents note continued: 32. Drug Hypersensitivity Reactions / Justinne Guyton
  Definition
  Pathogenesis
  Predisposing Factors
  Diagnosis
  Generalized Reactions
  Organ-Specific Reactions
  Pseudoallergic Reactions
  Prevention and Management of Allergic Reactions
  Key References and Websites
  33. Systemic Lupus Erythematosus / Mary A. Gutierrez
  General Principles
  Epidemiology
  Pathophysiology
  Classification Criteria
  Clinical Presentation
  Diagnosis
  Pharmacologic and Non-Pharmacologic Treatments
  Drug-Induced Lupus Erythematosus
  Investigational Agents
  Treatment Approaches
  Role for Pharmacists
  Key References and Websites
  34. Kidney and Liver Transplantation / Robert E. Dupuis
  Introduction to Transplantation
  Transplantation Immunology
  Immunosuppressive Agents
  Maintenance
  Induction
  Kidney Transplantation
  Liver Transplantation
  Key References and Websites
  SECTION 7 NUTRITION ISSUES / Susan L. Mayhew
  35. Basics of Nutrition and Patient Assessment / Jeff F. Binkley
  Nutrition Basics
  Malnutrition
  Nutrition Screening
  Patient Assessment: Woman with Crohn's Disease
  Key References and Websites
  36. Obesity / Kaelen C. Dunican
  Definitions
  Epidemiology
  Etiology and Pathophysiology
  Clinical Features
  Management and Treatment
  Key References and Websites
  37. Adult Enteral Nutrition / Jennifer H. Baggs
  Patient Selection and Route of Feeding
  Feeding Tube Placement and Site of Formula Delivery
  Formula Selection
  Initiation of Feedings
  Transition from Continuous to Intermittent/Bolus Feeding
  Fluid Provision
  Nutrition in Critical Illness
  Immune-Modulating Formulas
  Pulmonary Disease
  Renal Failure
  Monitoring Enteral Nutrition Support
  Medications and Enteral Nutrition by Tube
  Key References and Websites
  38. Adult Parenteral Nutrition / Richard S. Nicholas
  Venous Access Sites
  Components of Parenteral Nutrient Formulations
  Parenteral Nutrition
  Key References and Websites
  SECTION 8 DERMATOLOGIC DISORDERS / Timothy J. Ives
  39. Dermatotherapy and Drug-Induced Skin Disorders / Daniel R. Malcom
  Anatomy and Physiology of the Skin
  Inflammatory Lesions
  Dermatologic Drug Delivery Systems
  Assessing the Dermatologic Patient
  Xerosis
  Topical Corticosteroids
  Allergic Contact Dermatitis: Poison IVY, Poison Oak, or Poison Sumac
  Drug Eruptions
  Key References and Websites
  40. Acne / Kelly A. Mullican
  Definition and Epidemiology
  Pathophysiology
  Clinical Presentation
  Diagnosis
  Overview of Therapy
  Comedonal Acne Case
  Maculopapular Acne
  Nodular Acne Case
  Key References and Websites
  41. Psoriasis / Timothy J. Ives
  Epidemiology
  Treatment of Mild Psoriasis
  Treatment of Severe Psoriasis
  Systemic Pharmacotherapy
  Psoriatic Arthritis
  Key References and Websites
  42. Photosensitivity, Photoaging, and Burn Injuries / Timothy J. Ives
  Ultraviolet Radiation (UVR) Exposure
  Photoaging
  Burn Injuries
  Key References and Websites
  SECTION 9 RHEUMATIC AND MUSCULOSKELETAL DISEASES / Kamala M. Nola
  43. Osteoarthritis / Christopher M. Herndon
  Incidence, Prevalence, and Epidemiology
  Etiology
  Pathogenesis
  Overview of Drug Therapy
  Clinical Manifestations
  Treatment of Osteoarthritis
  Key References and Websites
  44. Rheumatoid Arthritis / Candace Tan
  Epidemiology
  Etiology
  Pathophysiology
  Extra-Articular Manifestations and Complications
  Juvenile Idiopathic Arthritis
  Key References and Websites
  45. Gout and Hyperuricemia / KarenBeth H. Bohan
  Pathophysiology
  Acute Gout
  Hyperuricemia
  Pharmacist's Role
  Key References and Websites
  46. Connective Tissue Disorders / Jonathan D. Ference
  Introduction
  General Signs and Symptoms
  Selected Connective Tissue Diseases
  Key References and Websites
  SECTION 10 WOMEN'S HEALTH / Trisha LaPointe
  47. Contraception / Shareen Y. El-Ibiary
  Epidemiology
  Hormonal Contraception Background and Pharmacology
  Combination Hormonal Contraceptives
  Contraceptive Patch and Ring
  Progestin-Only Contraceptives
  Intrauterine Device and Intrauterine System
  Other Nonhormonal Contraception
  Emergency Contraception
  Medical Abortion
  Key References and Websites
  48. Infertility / Erin C. Raney
  Introduction
  Pathophysiology and Diagnosis
  Treatment Approaches
  Key References and Websites
  49. Obstetric Drug Therapy / Trisha LaPointe
  Pregnancy
  Teratogenicity
  Management of Conditions in Pregnancy
  Urinary Tract Infections
  Diabetes Mellitus
  Hypertension and Preeclampsia
  Drug Therapy Management in Labor and Delivery
  Postpartum Hemorrhage
  Prevention of Rh D Alloimmunization
  Lactation
  Drug Excretion in Human Milk
  Acknowledgment
  Key References and Websites
  Medication Use in Pregnancy and Lactation
  General Information
  50. Disorders Related to the Menstrual Cycle / Karen M. Gunning
  Menstrual Cycle Physiology
  Polycystic Ovary Syndrome
  Dysmenorrhea
  Endometriosis
  Premenstrual Syndrome and Premenstrual Dysphoric Disorder
  Key References and Websites
  51. Transition Through Menopause / Trisha LaPointe
  Incidence, Prevalence, and Epidemiology
  Pathophysiology
  Clinical Presentation
  Key References and Websites
  SECTION 11 ENDOCRINE DISORDERS / Jennifer D. Goldman
  52. Thyroid Disorders / Betty J. Dong
  Overview
  Thyroid Function Tests
  Hypothyroidism
  Hyperthyroidism
  Drug-Induced Thyroid Disease
  Key References and Websites
  53. Diabetes Mellitus / David Schnee
  Definition, Classification, and Epidemiology
  Carbohydrate Metabolism
  Type 1 Diabetes
  Type 2 Diabetes
  Gestational Diabetes Mellitus
  Long-Term Complications
  Relationship of Glycemic Control to Microvascular and Macro vascular Disease
  Prevention of Type 1 and Type 2 Diabetes Mellitus
  Treatment
  Insulin
  Treatment of Type 1 Diabetes: Clinical Use of Insulin
  Diabetic Ketoacidosis
  Treatment of Type 2 Diabetes: Antidiabetic Agents
  Treatment of Patients with Type 2 Diabetes
  Drug-Induced Alterations in Glucose Homeostasis
  Acknowledgment
  Key References and Websites
  SECTION 12 EYE DISORDERS / Susan Jacobson
  54. Eye Disorders / Suellyn J. Sorensen
  Ocular Anatomy and Physiology
  Glaucoma
  Primary Open-Angle Glaucoma
  Angle-Closure Glaucoma
  Ocular Side Effects of Drugs
  Ocular Emergencies
  Common Ocular Disorders
  Ophthalmic Corticosteroids
  Systemic Side Effects from Ophthalmic Medication
  Ocular Nonsteroidal Anti-Inflammatory Drugs
  Ocular Herpes Simplex Virus Infections
  Age-Related Macular Degeneration
  Key References and Websites
  SECTION 13 NEUROLOGIC DISORDERS / Timothy E. Welty
  55. Pain and Its Management / Virginia L. Ghafoor
  Incidence, Prevalence, and Epidemiology
  Low Back Pain
  Neuropathic Pain and Postherpetic Neuralgia
  Central Neuropathic Pain: Poststroke Pain
  Functional Pain Syndromes (FPS)
  Cancer Pain and Symptom Management
  Key References and Websites
  56. Care of the Critically III Adult / John Marshall
  Home Medications in the Intensive Care Unit
  Pharmacokinetic Alterations in the ICU and Management Strategies
  Key References and Websites
  57. Multiple Sclerosis / Melody Ryan
  Epidemiology, Natural Course of the Disease, and Prognosis
  Pathophysiology
  XXXI Clinical Presentation
  Diagnosis
  Overview of Treatment
  Key References and Websites
  58. Headache / Steven J. Crosby
  Epidemiology and Description
  Migraine Headache
  Cluster Headache
  Tension-Type Headache
  Key References and Websites
  59. Parkinson's Disease and Other Movement Disorders / Natalie Whitmire
  Parkinson's Disease
  Restless Legs Syndrome and Periodic Limb Movements of Sleep
  Essential Tremor
  Key References and Websites
  60. Seizure Disorders / Brian K. Alldredge
  Clinical Assessment and Treatment of Epilepsy
  Women's Issues in Epilepsy
  Status Epilepticus
  Key References and Websites
  61. Ischemic and Hemorrhagic Stroke / Philip Grgurich
  Ischemic Stroke, Hemorrhagic Stroke, and Transient Ischemic Attacks
  Primary Prevention of Ischemic Stroke and Transient Ischemic Attacks
  Treatment of Acute Ischemic Stroke and TIA
  Secondary Prevention After Ischemic Stroke or TIA
  Spontaneous Intracerebral Hemorrhage
  Rehabilitation
  Key References and Websites
  SECTION 14 INFECTIOUS DISEASES / Caroline S. Zeind
  62. Principles of Infectious Diseases / B. Joseph Guglielmo
  Approaching the Problem
  Establishing the Presence of an Infection
  Establishing the Severity of an Infection
  Problems in the Diagnosis of an Infection
  Establishing the Site of the Infection
  Determining Likely Pathogens
  Microbiologic Tests and Susceptibility of Organisms
  Determination of Isolate Pathogenicity
  Antimicrobial Toxicities
  Antimicrobial Costs of Therapy
  Route of Administration
  Antimicrobial Dosing
  Pharmacokinetics and Pharmacodynamics
  Antimicrobial Failure
  Key References and Websites
  63. Antimicrobial Prophylaxis for Surgical Procedures / Daniel J. G. Thirion
  Risk Factors for Infection
  Classification of Surgical site infections
  Contents note continued: Principles of Surgical Antimicrobial Prophylaxis
  Optimizing Surgical Antimicrobial Prophylaxis
  Key References and Websites
  64. Vaccinations / Katherine Dillinger Ellis
  Vaccine Principles
  Guidelines
  Inactivated Vaccines
  Live Attenuated Vaccines
  Administration Techniques
  Legal Requirements
  Key References and Websites
  65. Central Nervous System Infections / Brian A. Potoski
  Review of Central Nervous System
  Meningitis
  Brain Abscess
  Key References and Websites
  66. Endocarditis / Annie Wong-Beringer
  Infective Endocarditis
  Streptococcus Viridans Group Endocarditis
  Staphylococcus Epidermidis: Prosthetic Valve Endocarditis
  Staphylococcus Aureus Endocarditis
  Enterococcal Endocarditis
  Fungal Endocarditis Caused by Candida Albicans
  Gram-Negative Bacillary Endocarditis Caused by Pseudomonas Aeruginosa
  Culture-Negative Endocarditis
  Prophylactic Therapy
  Key References and Websites
  67. Respiratory Tract Infections / Dinesh Yogaratnam
  Acute Bronchitis
  Acute Exacerbation of Chronic Obstructive Pulmonary Disease
  Prevention of Common Respiratory Infections by Vaccination
  Community-Acquired Pneumonia
  Hospital-Acquired Pneumonia, and Ventilator-Associated Pneumonia
  Key References and Websites
  68. Tuberculosis / Michael B. Kays
  History
  Treatment of Active Disease
  Treatment of Latent Tuberculosis Infection
  Adverse Drug Events
  Special Treatment Considerations
  Therapeutic Drug Monitoring
  Key References and Websites
  69. Infectious Diarrhea / David T. Bearden
  Prevalence and Etiology
  Definitions
  Pathogenesis
  Management Overview
  Evaluation and Treatment of Patients with Infectious Diarrhea
  Clinical Presentation
  Viral Gastroenteritis
  Vibrio Species
  Staphylococcus Aureus, Bacillus Cereus, and Clostridium Perfringens
  Cryptosporidium Parvum
  Salmonella
  Shigella Species
  Campylobacter Jejuni
  Travelers' Diarrhea
  Postinfectious Complications of TD
  Escherichia Coll 0157:H7
  Clostridium Difficile Infection
  Key References and Websites
  70. Intra-Abdominal Infections / Carrie A. Sincak
  Introduction
  Infections of the Biliary Tract
  Primary Peritonitis
  Secondary Peritonitis
  Infections After Abdominal Trauma and Postoperative Complications
  Key References and Websites
  71. Urinary Tract Infections / Douglas N. Fish
  Urinary Tract Infection
  Lower Urinary Tract Infection
  Treatment of Lower-Tract Infection in Renal Failure
  Recurrent Urinary Tract Infections
  Asymptomatic Bacteriuria
  Symptomatic Abacteriuria
  Hospital-Acquired Acute Urinary Tract Infection
  Prostatitis
  Key References and Websites
  72. Sexually Transmitted Diseases / Albert T. Bach
  Gonorrhea
  Pelvic Inflammatory Disease
  Complicated Gonorrhea
  Chlamydia Trachomatis
  Syphilis
  Chancroid
  Vaginitis
  Genital Herpes
  Genital Warts
  Key References and Websites
  73. Osteomyelitis and Septic Arthritis / Karyn M. Sullivan
  Osteomyelitis
  Septic Arthritis
  Key References and Websites
  74. Skin and Soft Tissue Infections / Kristine C. Willett
  Skin and Soft Tissue Infections
  Erysipelas
  Skin and Soft Tissue Infections in Diabetic Patients
  Animal Bite Wounds
  Human Bite Wounds
  Key References and Websites
  75. Prevention and Treatment of Infections in Neutropenic Cancer Patients / Richard H. Drew
  Risk Factors for Infection
  Most Common Pathogens
  Stratification for Risk of Infection
  Prophylaxis Against Infection
  Infections in Neutropenic Cancer Patients
  Empiric Antibiotic Therapy
  Antibiotic Dosing, Administration, and Monitoring Considerations
  Host Factors Influencing Response to Therapy
  Modifying Initial Empiric Antibiotic Therapy
  Antimicrobial Adjuvants
  Key References and Websites
  76. Pharmacotherapy of Human Immunodeficiency Virus Infection / Mackenzie L. Cottrell
  Introduction
  Epidemiology
  Pathophysiology
  Pharmacotherapy
  Diagnosis
  Surrogate Marker Data
  Antiretroviral Therapy
  Resistance, Viral Genotyping, Phenotyping, and Viral Fitness
  Special Circumstances
  Keeping Current
  Conclusion
  Key References and Websites
  77. Opportunistic Infections in HIV-infected Patients / Amanda H. Corbett
  Introduction
  Pneumocystis Jiroveci Pneumonia
  Toxoplasma Gondii Encephalitis
  Cytomegalovirus Disease
  Cryptococcosis
  Mycobacterium Tuberculosis
  Mycobacterium Avium Complex Disease
  Mucocutaneous Candidiasis
  Acknowledgments
  Key References and Websites
  78. Fungal Infections / Russell E. Lewis
  Mycology
  Antimycotics
  Superficial and Cutaneous Mycoses
  Subcutaneous Mycoses
  Systemic Mycoses
  Key References and Websites
  79. Viral Infections / Sandra Benavides
  Herpes Simplex Virus Infections
  Varicella-Zoster Infections
  Influenza
  Respiratory Syncytial Virus Infections
  Hantavirus
  West Nile Virus
  Severe Acute Respiratory Distress Syndrome
  Middle East Respiratory Syndrome
  Zika Virus
  Common Cold
  Key References and Websites
  80. Viral Hepatitis / Curtis D. Holt
  Causative Agents and Characteristics
  Hepatitis A Virus
  Hepatitis B Virus
  Hepatitis C Virus
  Hepatitis D Virus
  Hepatitis E Virus
  Summary
  Key References and Websites
  81. Parasitic Infections / Caroline S. Zeind
  Malaria
  Amebiasis
  Giardiasis
  Enterobiasis
  Cestodiasis
  Pediculosis
  Scabies
  Acknowledgment
  Key References and Websites
  82. Tick-Borne Diseases / Lin H. Chen
  Overview
  Lyme Disease
  Erythema Migrans
  Lyme Disease Treatment
  Relapsing Fever
  Other Bacterial Diseases: Tularemia
  Rickettsia: Rocky Mountain Spotted Fever, Rickettsia Parkeri Infection, Ehrlichiosis, and Anaplasmosis
  Protozoa: Babesiosis
  Viruses: Colorado Tick Fever, Tick-Borne Encephalitis, and Other Virally Mediated Tick-Borne Diseases
  Toxins: Tick Paralysis
  Mixed Infections
  Summary
  Acknowledgement
  Key References and Websites
  SECTION 15 PSYCHIATRIC DISORDERS AND SUBSTANCE ABUSE / Michael G. Carvalho
  83. Anxiety Disorders / Kristen N. Gardner
  Generalized Anxiety Disorder
  Panic Disorder
  Social Anxiety Disorder and Specific Phobias
  Post-Traumatic Stress Disorder and Acute Stress Disorder
  Obsessive-Compulsive Disorder
  Key References and Websites
  84. Sleep Disorders / Anna K. Morin
  Overview
  Circadian Rhythm and Sleep Cycles
  Neurochemistry of Sleep
  Wake Cycle
  Insomnia
  Insomnia in a Medically
  Patient
  Insomnia and Psychiatric Disorders
  Insomnia in the Elderly
  Pediatric Insomnia
  Pregnancy and Lactation
  Sleep Apnea
  Narcolepsy
  Acknowledgment
  Key References and Websites
  85. Schizophrenia / Justin C. Ellison
  Epidemiology
  Economic Burden
  Etiology
  Clinical Presentation
  Treatment
  Considerations in Specific Populations
  Key References and Websites
  86. Depressive Disorders / Michael C. Angelini
  Introduction
  Major Depressive Disorder
  Drug Management
  Key References and Websites
  87. Bipolar Disorders / Charles F. Caley
  Introduction
  Clinical Assessment
  Treatment of Acute Mania
  Treatment of Acute Bipolar Depression
  Maintenance Therapy of Bipolar Disorder
  Key References and Websites
  88. Developmental Disorders / Kimberly Lenz
  Epidemiology, Natural Course of the Disease, and Prognosis
  Pathophysiology: Disease Etiology, Anatomy, and Physiology
  Clinical Presentation
  Diagnosis
  Overview of Treatment
  Repetitive Behaviors
  Self-Injurious Behavior
  Anxiety/Depression
  Sleep
  89. Attention Deficit Hyperactivity Disorder in Children, Adolescents, and Adults / Joel Goldstein
  Epidemiology
  Pathophysiology
  Diagnosis, Signs, and Symptoms
  Comorbidity and Prognosis
  Treatment
  Adults with Attention Deficit Hyperactivity Disorder
  Key References and Websites
  90. Substance Use Disorders / Michael C. Angelini
  Substance Use Disorder
  Opioids
  Sedative-Hypnotics (Non-ETOH)
  Central Nervous System Stimulants
  Dissociative Drugs: Phencyclidine, Ketamine, and Dextromethorphan
  Hallucinogens
  Marijuana
  Inhalants
  Alcohol Use Disorders
  Alcohol Toxicity
  Alcohol Withdrawal
  Adjunctive Treatments
  Pharmacotherapy of Alcohol Dependence
  Disulfiram
  Acamprosate
  Naltrexone
  Combination Pharmacotherapy
  Acknowledgment
  Key References and Websites
  91. Tobacco Use and Dependence / Sarah E. McBane
  Epidemiology of Tobacco Use and Dependence
  Pharmacotherapy for Treating Tobacco Use and Dependence
  Key References and Websites
  SECTION 16 HEMATOLOGY AND ONCOLOGY / Christy S. Harris
  92. Anemias / Lisa A. Thompson
  Anemias
  Iron Deficiency Anemia
  Megaloblastic Anemias
  Sickle Cell Anemia
  Anemia of Inflammation
  Key References and Websites
  93. Neoplastic Disorders and Their Treatment: General Principles / Katherine Tipton Patel
  Introduction to Neoplastic Disorders
  Treatment
  Handling of Cytotoxic Drugs
  Key References and Websites
  94. Adverse Effects of Chemotherapy and Targeted Agents / Emily Mackler
  Common and Acute Toxicities
  Long-Term Complications of Anticancer Therapy
  Key References and Websites
  Contents note continued: 95. Pediatric Malignancies / Nicole A. Kaiser
  Pediatric Malignancies
  Pediatric Solid Tumors
  Acute Lymphoblastic Leukemia of Childhood
  Pediatric Non-Hodgkin Lymphoma
  Key References and Websites
  96. Adult Hematologic Malignancies / Katie A. Won
  Acute Myeloid Leukemia
  Chronic Myelogenous Leukemia
  Chronic Lymphocytic Leukemia
  Multiple Myeloma
  Lymphoma
  Key References and Websites
  97. Breast Cancer / Kellie Jones Weddle
  Breast Cancer
  Metastatic Breast Cancer
  Key References and Websites
  98. Lung Cancer / Sara K. Butler
  Lung Cancer
  Acknowledgment
  Key References and Websites
  99. Colorectal Cancer / Mario Blazer
  Colorectal Cancer
  Chemotherapy and Radiation for Early-Stage Rectal Cancer
  Acknowledgment
  Key References and Websites
  100. Prostate Cancer / Christy S. Harris
  Incidence, Prevalence, and Epidemiology
  Pathophysiology
  Clinical Presentation and Diagnosis
  Overview of Treatment
  Risk Factors
  Screening
  Prognostic Factors
  Treatment
  Castration-Resistant Prostate Cancer
  Prevention
  Survivorship
  Key References and Websites
  101. Hematopoietic Cell Transplantation / Valerie Relias
  Overview
  Autologous Hematopoietic Stem Cell Transplantation
  Allogeneic Hematopoietic Stem Cell Transplantation
  Complications Associated with Hematopoietic Cell Transplantation
  Graft-Versus-Host Disease
  Infectious Complications
  Issues of Survivorship After Hematopoietic Cell Transplantation
  Key References and Websites
  SECTION 17 PEDIATRICS / Marcia L. Buck
  102. Pediatric Pharmacotherapy / Marcia L. Buck
  Growth and Development During Childhood
  Pediatric Pharmacokinetic Differences
  Pediatric Pharmacodynamic Differences
  Medication Dosing in Children
  Preventing Medication Errors in Children
  Increasing Availability of Pediatric Medication Information
  Key References and Websites
  103. Pediatric Fluid, Electrolytes, and Nutrition / Jennifer W. Chow
  Fluid and Electrolyte Maintenance
  Infant Enteral Nutrition
  Key References and Websites
  104. Common Pediatric Illnesses / Bethany Ibach
  Administering Medication to Children
  Infant Care
  Viral Gastroenteritis
  Gastroesophageal Reflux
  Common Pediatric Infections
  Key References and Websites
  105. Neonatal Therapy / Kirsten H. Ohler
  Neonatal Therapy
  Respiratory Distress Syndrome
  Bronchopulmonary Dysplasia
  Patent Ductus Arteriosus
  Necrotizing Enterocolitis
  Neonatal Sepsis and Meningitis
  Congenital Infections
  Apnea of Prematurity
  Neonatal Seizures
  Key References and Websites
  106. Care of the Critically III Child / Marcia L. Buck
  Pediatric Cardiopulmonary Resuscitation
  Respiratory Distress
  Medications for Intubation and Mechanical Ventilation
  Pediatric Shock
  Sepsis and Septic Shock in Infants and Children
  Initial Management of Pediatric Septic Shock
  Cardiovascular Drug Therapy
  Corticosteroid Administration in Pediatric Septic Shock
  Adjunctive Therapies
  Congenital Heart Disease
  Pediatric Traumatic Brain Injury
  Key References and Websites
  SECTION 18 GERIATRIC THERAPY / Judith L. Beizer
  107. Geriatric Drug Use / Kristin Zimmerman
  Demographic and Economic Considerations
  Age-Related Physiologic, Pharmacokinetic, and Pharmacodynamic Changes
  Pharmacodynamic Changes
  Problems Associated with Drug Use in Older Adults
  Disease-Specific Geriatric Drug Therapy
  Long-Term Care Facilities
  Key References and Websites
  108. Geriatric Neurocognitive Disorders / Bradley R. Williams
  Geriatric Dementias
  Alzheimer's Disease
  Lewy Body Dementias
  Vascular Dementia (VaD)
  Behavioral Disturbances in Dementia
  Key References and Websites
  109. Geriatric Urologic Disorders / Tran H. Tran
  Urinary Incontinence
  Benign Prostatic Hyperplasia
  Sexual Dysfunction
  Key References and Websites
  110. Osteoporosis / Mary-Kathleen Grams
  Incidence, Prevalence, and Epidemiology
  Key References and Websites.