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    Click chemistry for biotechnology and materials science / edited by Joerg Lahann.

    • Title:Click chemistry for biotechnology and materials science / edited by Joerg Lahann.
    •    
    • Other Contributors/Collections:Lahann, Joerg.
    • Published/Created:Chichester, West Sussex : Wiley, 2009.
    • Holdings

       
    • Library of Congress Subjects:Biotechnology.
      Materials science.
      Combinatorial chemistry.
      Macromolecules--Synthesis.
    • Medical Subjects: Biotechnology
    • Description:xvii, 411 pages : illustrations (some color) ; 26 cm.
    • Summary:Mimicking natural biochemical processes, click chemistry is a modular approach to organic synthesis, joining together small chemical units quickly, efficiently and predictably. In contrast to complex traditional synthesis, click reactions offer high selectivity and yields, near-perfect reliability and exceptional tolerance towards a wide range of functional groups and reaction conditions. These 'spring loaded' reactions are achieved by using a high thermodynamic driving force, and are attracting tremendous attention throughout the chemical community. Originally introduced with the focus on drug discovery, the concept has been successfully applied to materials science, polymer chemistry and biotechnology.
    • Notes:Includes bibliographical references and index.
    • ISBN:9780470699706 (hbk.)
      0470699701
    • Contents:1. Click Chemistry: A Universal Ligation Strategy for Biotechnology and Materials Science / Joerg Lahann
      2. Common Synthons for Click Chemistry in Biotechnology / Christine Schilling, Nicole Jung and Stefan Btase
      3. Copper-free Click Chemistry / Jeremy M. Baskin and Carolyn R. Bertozzi
      4. Protein and Peptide Conjugation to Polymers and Surfaces Using Oxime Chemistry / Heather D. Maynard, Rebecca M. Broyer and Christopher M. Kolodziej
      5. Role of Click Chemistry in Polymer Synthesis / Jean-Francois Lutz and Brent S. Sumerlin
      6. Blocks, Stars and Combs: Complex Macromolecular Architecture Polymers via Click Chemistry / Sebastian Sinnwell, Andrew J. Inglis, Martina H. Stenzel and Christopher Barner-Kowollik
      7. Click Chemistry on Supramolecular Materials / Wolfgang H. Binder and Robert Sachsenhofer
      8. Dendrimer Synthesis and Functionalization by Click Chemistry for Biomedical Applications / Daniel Q. McNerny, Douglas G. Mullen, Istvan J. Majoros, Mark M. Banaszak Holl and James R. Baker, Jr.
      9. Reversible Diels-Alder Cycloaddition for the Design of Multifunctional Network Polymers / Amy M. Peterson and Giuseppe R. Palmese
      10. Click Chemistry in the Preparation of Biohybrid Materials / Heather J. Kitto, Jan Lauko, Floris P. J. T. Rutjes and Alan E. Rowan
      11. Functional Nanomaterials using the Cu-catalyzed Huisgen Cycloaddition Reaction / Sander S. van Berkel, Arnold W. G. Nijhuis, Dennis W. P. M. Lowik and Jan C. M. van Hest
      12. Copper-catalyzed 'Click' Chemistry for Surface Engineering / Himabindu Nandivada and Joerg Lahann
      13. Click Chemistry in Protein Engineering, Design, Detection and Profiling / Daniela C. Dieterich and A. James Link
      14. Fluorogenic Copper(I)-catalyzed Azide-Alkyne Cycloaddition Reactions Reactions and their Applications in Bioconjugation / Celine Le Droumaguet and Qian Wang
      15. Synthesis and Functionalization of Biomolecules via Click Chemistry / Christine Schilling, Nicole Jung and Stefan Brase
      16. Unprecedented Electro-optic Properties in Polymers and Dendrimers Enabled by Click Chemistry Based on the Diels-Alder Reactions / Jingdong Luo, Tae-Dong Kim and Alex K.-Y Jen.
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