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    Essentials of glycobiology / edited by Ajit Varki [and eleven others].

    • Title:Essentials of glycobiology / edited by Ajit Varki [and eleven others].
    •    
    • Other Contributors/Collections:Varki, Ajit, editor.
    • Published/Created:Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, [2017]
    • Holdings

       
    • Library of Congress Subjects:Glycoproteins.
      Glycosylation.
      Glycomics.
      Molecular biology.
    • Medical Subjects: Glycoproteins
      Glycosyltransferases
      Glycosylation
      Glycomics
      Molecular Biology
    • Edition:Third edition.
    • Description:xxix, 823 pages : illustrations (some color) ; 29 cm
    • Summary:"Defined in the broadest sense, Glycobiology is the study of the structure, biosynthesis, biology, and evolution of saccharides (sugar chains or glycans) that are widely distributed in nature in all living life forms. Glycobiology is now one of the more rapidly growing fields in the natural sciences, with broad relevance to many areas of basic research, biomedicine, and biotechnology. The field includes the chemistry of carbohydrates, the enzymology of glycan formation and degradation, the recognition of glycans by specific proteins, roles of glycans in complex biological systems, and their analysis or manipulation by various techniques. The third edition of this primary textbook in the field continues in the prior tradition, seeking to provide basic overview of Glycobiology, directed towards the advanced undergraduate or the beginning graduate-level student of molecular and cellular biology and biomedicine. "--Amazon.com.
    • Notes:Includes bibliographical references and index.
    • ISBN:9781621821328 hardcover
      1621821323 hardcover
    • Contents:General principles. Historical background and overview / Ajit Varki and Stuart Kornfeld
      Monosaccharide diversity / Peter H. Seeberger
      Oligosaccharides and polysaccharides / James H. Prestegard, Jian Liu, and Göran Widmalm
      Cellular organization of glycosylation / Karen J. Colley, Ajit Varki, and Taroh Kinoshita
      Glycosylation precursors / Hudson H. Freeze, Gerald W. Hart, and Ronald L. Schnaar
      Glycosyltransferases and glycan-processing enzymes / James M. Rini and Jeffrey D. Esko
      Biological functions of glycans / Ajit Varki and Pascal Gagneux
      A genomic view of glycobiology / Bernard Henrissat, Avadesha Surolia, and Pamela Stanley
      Structure and biosynethis. N-glycans / Pamela Stanley, Naoyuki Taniguchi, and Markus Aebi
      O-GalNAc glycans / Inka Brockhausen and Pamela Stanley
      Glycosphingolipids / Ronald L. Schnaar and Taroh Kinoshita
      Glycosylphosphatidylinositol anchors / Michael A.J. Ferguson, Gerald W. Hart, and Taroh Kinoshita
      Other classes of eukaryotic glycans / Robert S. Haltiwanger, Lance Wells, Hudson H. Freeze, and Pamela Stanley
      Structures common to different glycans / Pamela Stanley and Richard D. Cummings
      Sialic acids and other nonulosonic acids / Ajit Varki, Ronald L. Schnaar, and Roland Schauer
      Hyaluronan / Vincent Hascall and Jeffrey D. Esko
      Proteoglycans and sulfated glycosaminoglycans / Ulf Lindahl, John Couchman, Koji Kimata, and Jeffrey D. Esko
      Nucleocytoplasmic glycosylation / Christopher M. West and Gerald W. Hunt
      The O-GlcNAc modification / Natasha Zachara, Yoshihiro Akimoto, and Gerald W. Hart
      Glycans in evolution and development. Evolution of glycan diversity / Pascal Gagneux, Markus Aebi, and Ajit Varki
      Eubacteria / Chris Whitfield, Christine M. Szymanski, and Markus Aebi
      Archaea / Sonja Albers, Jerry Eichler, and Markus Aebi
      Fungi / Tamara L. Doering, Richard D. Cummings, and Markus Aebi
      Viridiplantae and algae / Malcolm A. O'Neill, Alan G. Darvill, Marilynn E. Etzler, Debra Mohnen, and Serge Perez
      Nematoda / Iain B.H. Wilson, Richard D. Cummings, and Markus Aebi
      Arthropoda / Michael Tiemeyer, Hiroshi Nakato, and Jeffrey D. Esko
      Deuterostomes / Michael Pierce and Pamela Stanley
      Glycan-binding proteins. Discovery and classification of glycan-binding proteins / Maureen E. Taylor, Kurt Drickamer, Ronald L. Schnaar, Marilynn E. Etzler, and Ajit Varki
      Principles of glycan recognition / Richard D. Cummings, Ronald L. Schnaar, Jeffrey D. Esko, Kurt Drickamer, and Maureen E. Taylor
      Structural biology of glycan recognition / Anne Imberty and James H. Prestegard
      R-type lectins / Richard D. Cummings and Ronald L. Schnaar
      L-type lectins / Richard D. Cummings, Marilynn E. Etzler, and Avadhesha Surolia
      P-type lectins / Ajit Varki and Stuart Kornfeld
      C-type lectins / Richard Cummings and Rodger P. McEver
      I-type lectins / Ajit Varki, Ronald L. Schnaar, and Paul R. Crocker
      Galectins / Richard D. Cummings, Fu-Tong Liu, and Gerardo R. Vasta
      Microbial lectins: hemagglutinins, adhesins, and toxins / Victor Nizet, Ajit Varki, and Markus Aebi
      Proteins that bind sulfated glycosaminoglycans / Jeffrey D. Esko, James H. Prestegard, and Robert J. Linhardt
      Glycans in physiology and disease. Glycans in glycoprotein quality control / Armando Parodi, Richard D. Cummings, and Markus Aebi
      Free glycans as signaling molecules / Malcolm A. O'Neill, Alan G. Darvill, Marilynn E. Etzler, and Jeffrey D. Esko
      Glycans in systemic physiology / Hudson H. Freeze, Linda Baum, and Ajit Varki
      Bacterial and viral infections / Christine M. Szymanski, Ronald L. Schnaar, and Markus Aebi
      Parasitic infections / Richard D. Cummings and Irma van Die
      Genetic disorders of glycan degradation / Hudson H. Freeze, Taroh Kinoshita, and Ronald L. Schnaar
      Genetic disorders of glycosylation / Hudson H. Freeze, Harry Schachter, and Taroh Kinoshita
      Glycans in acquired human diseases / Hudson H. Freeze, Taroh Kinoshita, and Ajit Varka
      Glycosylation changes in cancer / Ajit Varki, Reiji Kannagi, Bryan Toole, and Pamela Stanley
      Methods and applications. Glycan-recognizing probes as tools / Richard D. Cummings, Alan G. Darvill, Marilynn E. Etzler, and Michael G. Hahn
      Glycosylation mutants of cultured mammalian cells / Jeffrey D. Esko and Pamela Stanley
      Structural analysis of glycans / Barbara Mulloy, Anne Dell, Pamela Stanley, and James H. Prestegard
      Glycomics and glycoproteomics / Pauline Rudd, Niclas G. Karlsson, Kay-Hooi Khoo, and Nicolle H. Packer
      Glycoinformatics / Matthew P. Campbell, Kiyoko F. Aoki-Kinoshita, Frederique Lisacek, William S. York, and Nicolle H. Packer
      Chemical synthesis of glycans and glycoconjugates / Peter H. Seeberger and Hermen S. Overkleeft
      Chemoenzymatic synthesis of glycans and glycoconjugates / Hermen S. Overkleeft and Peter H. Seeberger
      Chemical tools for inhibiting glycosylation / Jeffrey D. Esko, Carolyn Bertozzi, and Ronald L. Schnaar
      Glycosylation engineering / Henrik Clausen, Hans H. Wandall, Catharina Steentoft, Pamela Stanley, and Ronald L. Schnaar
      Glycans in biotechnology and the pharmaceutical industry / Peter H. Seeberger and Richard D. Cummings
      Glycans in nanotechnology / Soledad Penadés, Benjamin G. Davis, and Peter H. Seeberger
      Glycans in bioenergy and materials science / Malcolm A. O'Neill, Robert J. Moon, William S. York, and Alan G. Darvill
      Future directions in glycosciences / Gerald W. Hart and Ajit Varki.
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